Chimeric HIV-1 Envelope Glycoproteins with Potent Intrinsic Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Activity*

HIV-1 acquisition can be prevented by broadly neutralizing antibodies (BrNAbs) that target the envelope glycoprotein complex (Env). An ideal vaccine should therefore be able to induce BrNAbs that can provide immunity over a prolonged period of time, but the low intrinsic immunogenicity of HIV-1 Env...

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Autores principales: Isik, Gözde, van Montfort, Thijs, Boot, Maikel, Cobos Jiménez, Viviana, Kootstra, Neeltje A., Sanders, Rogier W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615126/
https://ncbi.nlm.nih.gov/pubmed/23565193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060126
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