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An HIV-1 Envelope Glycoprotein Trimer with an Embedded IL-21 Domain Activates Human B Cells

Broadly neutralizing antibodies (bNAbs) that target the HIV-1 envelope glycoproteins (Env) can prevent virus acquisition, but several Env properties limit its ability to induce an antibody response that is of sufficient quantity and quality. The immunogenicity of Env can be increased by fusion to co...

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Detaylı Bibliyografya
Asıl Yazarlar: Isik, Gözde, Chung, Nancy P. Y., van Montfort, Thijs, Menis, Sergey, Matthews, Katie, Schief, William R., Moore, John P., Sanders, Rogier W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691133/
https://ncbi.nlm.nih.gov/pubmed/23826263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067309
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