Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer

The trimeric envelope (Env) spike is the focus of vaccine design efforts aimed at generating broadly neutralizing antibodies (bNAbs) to protect against HIV-1 infection. Three recent developments have facilitated a thorough investigation of the antigenic structure of the Env trimer: 1) the isolation...

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Udgivet i:PLoS Pathog
Main Authors: Derking, Ronald, Ozorowski, Gabriel, Sliepen, Kwinten, Yasmeen, Anila, Cupo, Albert, Torres, Jonathan L., Julien, Jean-Philippe, Lee, Jeong Hyun, van Montfort, Thijs, de Taeye, Steven W., Connors, Mark, Burton, Dennis R., Wilson, Ian A., Klasse, Per-Johan, Ward, Andrew B., Moore, John P., Sanders, Rogier W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373910/
https://ncbi.nlm.nih.gov/pubmed/25807248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004767
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