Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

Generating neutralizing antibodies (nAbs) is a major goal of many current HIV-1 vaccine efforts. To be of practical value, these nAbs must be both potent and cross-reactive in order to be capable of preventing the transmission of the highly diverse and generally neutralization resistant (Tier-2) HIV...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Hu, Joyce K., Crampton, Jordan C., Cupo, Albert, Ketas, Thomas, van Gils, Marit J., Sliepen, Kwinten, de Taeye, Steven W., Sok, Devin, Ozorowski, Gabriel, Deresa, Isaiah, Stanfield, Robyn, Ward, Andrew B., Burton, Dennis R., Klasse, Per Johan, Sanders, Rogier W., Moore, John P., Crotty, Shane
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580201/
https://ncbi.nlm.nih.gov/pubmed/26246566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-15
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