Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

Generating neutralizing antibodies (nAbs) is a major goal of many current HIV-1 vaccine efforts. To be of practical value, these nAbs must be both potent and cross-reactive in order to be capable of preventing the transmission of the highly diverse and generally neutralization resistant (Tier-2) HIV...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Hu, Joyce K., Crampton, Jordan C., Cupo, Albert, Ketas, Thomas, van Gils, Marit J., Sliepen, Kwinten, de Taeye, Steven W., Sok, Devin, Ozorowski, Gabriel, Deresa, Isaiah, Stanfield, Robyn, Ward, Andrew B., Burton, Dennis R., Klasse, Per Johan, Sanders, Rogier W., Moore, John P., Crotty, Shane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
Onderwerpen:
Vaccines and Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580201/
https://ncbi.nlm.nih.gov/pubmed/26246566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-15
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