Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

Generating neutralizing antibodies (nAbs) is a major goal of many current HIV-1 vaccine efforts. To be of practical value, these nAbs must be both potent and cross-reactive in order to be capable of preventing the transmission of the highly diverse and generally neutralization resistant (Tier-2) HIV...

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Vydáno v:J Virol
Hlavní autoři: Hu, Joyce K., Crampton, Jordan C., Cupo, Albert, Ketas, Thomas, van Gils, Marit J., Sliepen, Kwinten, de Taeye, Steven W., Sok, Devin, Ozorowski, Gabriel, Deresa, Isaiah, Stanfield, Robyn, Ward, Andrew B., Burton, Dennis R., Klasse, Per Johan, Sanders, Rogier W., Moore, John P., Crotty, Shane
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580201/
https://ncbi.nlm.nih.gov/pubmed/26246566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-15
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