Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

Generating neutralizing antibodies (nAbs) is a major goal of many current HIV-1 vaccine efforts. To be of practical value, these nAbs must be both potent and cross-reactive in order to be capable of preventing the transmission of the highly diverse and generally neutralization resistant (Tier-2) HIV...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hu, Joyce K., Crampton, Jordan C., Cupo, Albert, Ketas, Thomas, van Gils, Marit J., Sliepen, Kwinten, de Taeye, Steven W., Sok, Devin, Ozorowski, Gabriel, Deresa, Isaiah, Stanfield, Robyn, Ward, Andrew B., Burton, Dennis R., Klasse, Per Johan, Sanders, Rogier W., Moore, John P., Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580201/
https://ncbi.nlm.nih.gov/pubmed/26246566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-15
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