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Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms
The repeating structural unit of metazoan chromatin is the chromatosome, a nucleosome bound to a linker histone, H1. There are 11 human H1 isoforms with diverse cellular functions, but how they interact with the nucleosome remains elusive. Here, we determined the cryoelectron microscopy (cryo-EM) st...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7796963/ https://ncbi.nlm.nih.gov/pubmed/33238161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.038 |
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