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Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery
Energy-dependent Lon proteases play a key role in cellular regulation by degrading short-lived regulatory proteins and misfolded proteins in the cell. The structure of the catalytically inactive S679A mutant of Escherichia coli LonA protease (EcLon) has been determined by cryo-EM at the resolution o...
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| Pubblicato in: | Curr Res Struct Biol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8244335/ https://ncbi.nlm.nih.gov/pubmed/34235464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crstbi.2019.10.001 |
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