Slicing a protease: Structural features of the ATP-dependent Lon proteases gleaned from investigations of isolated domains

ATP-dependent Lon proteases are multi-domain enzymes found in all living organisms. All Lon proteases contain an ATPase domain belonging to the AAA(+) superfamily of molecular machines and a proteolytic domain with a serine-lysine catalytic dyad. Lon proteases can be divided into two subfamilies, Lo...

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Detalhes bibliográficos
Main Authors: Rotanova, Tatyana V., Botos, Istvan, Melnikov, Edward E., Rasulova, Fatima, Gustchina, Alla, Maurizi, Michael R., Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242575/
https://ncbi.nlm.nih.gov/pubmed/16877706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.052069306
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