Hearing Loss and Hair Cell Death in Mice Given the Cholesterol-Chelating Agent Hydroxypropyl-β-Cyclodextrin

Cyclodextrins are sugar compounds that are increasingly finding medicinal uses due to their ability to complex with hydrophobic molecules. One cyclodextrin in particular, 2-hydroxypropyl-β-cyclodextrin (HPβCD), is used as a carrier to solubilize lipophilic drugs and is itself being considered as a t...

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Главные авторы: Crumling, Mark A., Liu, Liqian, Thomas, Paul V., Benson, Jennifer, Kanicki, Ariane, Kabara, Lisa, Hälsey, Karin, Dolan, David, Duncan, R. Keith
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532434/
https://ncbi.nlm.nih.gov/pubmed/23285273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053280
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