COVID-19: Knowns, Unknowns, and Questions

di Weston, Stuart, Frieman, Matthew B.
Pubblicato in mSphere (2020)

Respiratory Viruses

di Weston, Stuart, Frieman, Matthew B.
Pubblicato in Encyclopedia of Microbiology (2019)

A Membrane Topology Model for Human Interferon Inducible Transmembrane Protein 1

di Weston, Stuart, Czieso, Stephanie, White, Ian J., Smith, Sarah E., Kellam, Paul, Marsh, Mark
Pubblicazione 2014

A Yeast Suppressor Screen Used To Identify Mammalian SIRT1 as a Proviral Factor for Middle East Respiratory Syndrome Coronavirus Replication

di Weston, Stuart, Matthews, Krystal L., Lent, Rachel, Vlk, Alexandra, Haupt, Rob, Kingsbury, Tami, Frieman, Matthew B.
Pubblicato in J Virol (2019)

Coronavirus interactions with the cellular autophagy machinery

di Miller, Katelyn, McGrath, Marisa E., Hu, Zhiqiang, Ariannejad, Sohha, Weston, Stuart, Frieman, Matthew, Jackson, William T
Pubblicato in Autophagy (2020)

Alphavirus Restriction by IFITM Proteins

di Weston, Stuart, Czieso, Stephanie, White, Ian J., Smith, Sarah E., Wash, Rachael S., Diaz‐Soria, Carmen, Kellam, Paul, Marsh, Mark
Pubblicato in Traffic (2016)

Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs against SARS-CoV-2 In Vitro and SARS-CoV In Vivo

di Weston, Stuart, Coleman, Christopher M., Haupt, Robert, Logue, James, Matthews, Krystal, Li, Yize, Reyes, Hanako M., Weiss, Susan R., Frieman, Matthew B.
Pubblicato in J Virol (2020)

Heat shock protein 90 controls HIV-1 reactivation from latency

di Anderson, Ian, Low, Jun Siong, Weston, Stuart, Weinberger, Michael, Zhyvoloup, Alexander, Labokha, Aksana A., Corazza, Gianmarco, Kitson, Russell A., Moody, Christopher J., Marcello, Alessandro, Fassati, Ariberto
Pubblicazione 2014

Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain

di Benfield, Camilla TO, MacKenzie, Farrell, Ritzefeld, Markus, Mazzon, Michela, Weston, Stuart, Tate, Edward W, Teo, Boon Han, Smith, Sarah E, Kellam, Paul, Holmes, Edward C, Marsh, Mark
Pubblicato in Life Sci Alliance (2019)

Correction: Bat IFITM3 restriction depends on S-palmitoylation and a polymorphic site within the CD225 domain

di Benfield, Camilla TO, MacKenzie, Farrell, Ritzefeld, Markus, Mazzon, Michela, Weston, Stuart, Tate, Edward W, Teo, Boon Han, Smith, Sarah E, Kellam, Paul, Holmes, Edward C, Marsh, Mark
Pubblicato in Life Sci Alliance (2020)

The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses

di Weston, Stuart, Baracco, Lauren, Keller, Chloe, Matthews, Krystal, McGrath, Marisa E., Logue, James, Liang, Janie, Dyall, Julie, Holbrook, Michael R., Hensley, Lisa E., Jahrling, Peter B., Yu, Wenbo, MacKerell, Alexander D., Frieman, Matthew B.
Pubblicato in Proc Natl Acad Sci U S A (2020)

Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection

di Schultz, David C., Johnson, Robert M., Ayyanathan, Kasirajan, Miller, Jesse, Whig, Kanupriya, Kamalia, Brinda, Dittmar, Mark, Weston, Stuart, Hammond, Holly L., Dillen, Carly, Castellana, Lauren, Lee, Jae Seung, Li, Minghua, Lee, Emily, Constant, Samuel, Ferrer, Marc, Thaiss, Christoph A., Frieman, Matthew B., Cherry, Sara
Pubblicato in bioRxiv (2021)

Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine

di Keech, Cheryl, Albert, Gary, Cho, Iksung, Robertson, Andreana, Reed, Patricia, Neal, Susan, Plested, Joyce S., Zhu, Mingzhu, Cloney-Clark, Shane, Zhou, Haixia, Smith, Gale, Patel, Nita, Frieman, Matthew B., Haupt, Robert E., Logue, James, McGrath, Marisa, Weston, Stuart, Piedra, Pedro A., Desai, Chinar, Callahan, Kathleen, Lewis, Maggie, Price-Abbott, Patricia, Formica, Neil, Shinde, Vivek, Fries, Louis, Lickliter, Jason D., Griffin, Paul, Wilkinson, Bethanie, Glenn, Gregory M.
Pubblicato in N Engl J Med (2020)

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

di Puhl, Ana C., Fritch, Ethan James, Lane, Thomas R., Tse, Longping V., Yount, Boyd L., Sacramento, Carol Queiroz, Tavella, Tatyana Almeida, Costa, Fabio Trindade Maranhão, Weston, Stuart, Logue, James, Frieman, Matthew, Premkumar, Lakshmanane, Pearce, Kenneth H., Hurst, Brett L., Andrade, Carolina Horta, Levi, James A., Johnson, Nicole J., Kisthardt, Samantha C., Scholle, Frank, Souza, Thiago Moreno L., Moorman, Nathaniel John, Baric, Ralph S., Madrid, Peter, Ekins, Sean
Pubblicato in bioRxiv (2020)

SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice

di Tian, Jing-Hui, Patel, Nita, Haupt, Robert, Zhou, Haixia, Weston, Stuart, Hammond, Holly, Logue, James, Portnoff, Alyse D., Norton, James, Guebre-Xabier, Mimi, Zhou, Bin, Jacobson, Kelsey, Maciejewski, Sonia, Khatoon, Rafia, Wisniewska, Malgorzata, Moffitt, Will, Kluepfel-Stahl, Stefanie, Ekechukwu, Betty, Papin, James, Boddapati, Sarathi, Jason Wong, C., Piedra, Pedro A., Frieman, Matthew B., Massare, Michael J., Fries, Louis, Bengtsson, Karin Lövgren, Stertman, Linda, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale
Pubblicato in Nat Commun (2021)

Genetic and structural basis for recognition of SARS-CoV-2 spike protein by a two-antibody cocktail

di Dong, Jinhui, Zost, Seth, Greaney, Allison, Starr, Tyler N, Dingens, Adam S, Chen, Elaine C, Chen, Rita, Case, Brett, Sutton, Rachel, Gilchuk, Pavlo, Rodriguez, Jessica, Armstrong, Erica, Gainza, Christopher, Nargi, Rachel, Binshtein, Elad, Xie, Xuping, Zhang, Xianwen, Shi, Pei-Yong, Logue, James, Weston, Stuart, McGrath, Marisa, Frieman, Matthew, Brady, Tyler, Tuffy, Kevin, Bright, Helen, Loo, Yueh-Ming, McvTamney, Patrick, Esser, Mark, Carnahan, Robert, Diamond, Michael, Bloom, Jesse, Crowe, James E
Pubblicato in bioRxiv (2021)

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV-2 and Potential Mechanisms

di Puhl, Ana C., Fritch, Ethan J., Lane, Thomas R., Tse, Longping V., Yount, Boyd L., Sacramento, Carolina Q., Fintelman-Rodrigues, Natalia, Tavella, Tatyana Almeida, Maranhão Costa, Fabio Trindade, Weston, Stuart, Logue, James, Frieman, Matthew, Premkumar, Lakshmanane, Pearce, Kenneth H., Hurst, Brett L., Andrade, Carolina Horta, Levi, James A., Johnson, Nicole J., Kisthardt, Samantha C., Scholle, Frank, Souza, Thiago Moreno L., Moorman, Nathaniel John, Baric, Ralph S., Madrid, Peter B., Ekins, Sean
Pubblicato in ACS Omega (2021)

Functional landscape of SARS-CoV-2 cellular restriction

di Martin-Sancho, Laura, Lewinski, Mary K., Pache, Lars, Stoneham, Charlotte A., Yin, Xin, Becker, Mark E., Pratt, Dexter, Churas, Christopher, Rosenthal, Sara B., Liu, Sophie, Weston, Stuart, De Jesus, Paul D., O’Neill, Alan M., Gounder, Anshu P., Nguyen, Courtney, Pu, Yuan, Curry, Heather M., Oom, Aaron L., Miorin, Lisa, Rodriguez-Frandsen, Ariel, Zheng, Fan, Wu, Chunxiang, Xiong, Yong, Urbanowski, Matthew, Shaw, Megan L., Chang, Max W., Benner, Christopher, Hope, Thomas J., Frieman, Matthew B., García-Sastre, Adolfo, Ideker, Trey, Hultquist, Judd F., Guatelli, John, Chanda, Sumit K.
Pubblicato in Mol Cell (2021)

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

di Hansen, Johanna, Baum, Alina, Pascal, Kristen E., Russo, Vincenzo, Giordano, Stephanie, Wloga, Elzbieta, Fulton, Benjamin O., Yan, Ying, Koon, Katrina, Patel, Krunal, Chung, Kyung Min, Hermann, Aynur, Ullman, Erica, Cruz, Jonathan, Rafique, Ashique, Huang, Tammy, Fairhurst, Jeanette, Libertiny, Christen, Malbec, Marine, Lee, Wen-yi, Welsh, Richard, Farr, Glen, Pennington, Seth, Deshpande, Dipali, Cheng, Jemmie, Watty, Anke, Bouffard, Pascal, Babb, Robert, Levenkova, Natasha, Chen, Calvin, Zhang, Bojie, Romero Hernandez, Annabel, Saotome, Kei, Zhou, Yi, Franklin, Matthew, Sivapalasingam, Sumathi, Lye, David Chien, Weston, Stuart, Logue, James, Haupt, Robert, Frieman, Matthew, Chen, Gang, Olson, William, Murphy, Andrew J., Stahl, Neil, Yancopoulos, George D., Kyratsous, Christos A.
Pubblicato in Science (2020)

Alum:CpG adjuvant enables SARS-CoV-2 RBD-induced protection in aged mice and synergistic activation of human elder type 1 immunity

di Nanishi, Etsuro, Borriello, Francesco, O’Meara, Timothy R., McGrath, Marisa E., Saito, Yoshine, Haupt, Robert E., Seo, Hyuk-Soo, van Haren, Simon D., Brook, Byron, Chen, Jing, Diray-Arce, Joann, Doss-Gollin, Simon, Leon, Maria De, Chew, Katherine, Menon, Manisha, Song, Kijun, Xu, Andrew Z., Caradonna, Timothy M., Feldman, Jared, Hauser, Blake M., Schmidt, Aaron G., Sherman, Amy C., Baden, Lindsey R., Ernst, Robert K., Dillen, Carly, Weston, Stuart M., Johnson, Robert M., Hammond, Holly L., Mayer, Romana, Burke, Allen, Bottazzi, Maria E., Hotez, Peter J., Strych, Ulrich, Chang, Aiquan, Yu, Jingyou, Barouch, Dan H., Dhe-Paganon, Sirano, Zanoni, Ivan, Ozonoff, Al, Frieman, Matthew B., Levy, Ofer, Dowling, David J.
Pubblicato in bioRxiv (2021)