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Where does amantadine bind to the influenza virus M2 proton channel?
Structures of the influenza A virus M2 proton channel have been determined by X-ray crystallography in the open conformation, and by NMR in the closed state. Whereas the X-ray structure shows a single inhibitor molecule in the middle of the channel, four inhibitor molecules bind the channel’s outer...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919587/ https://ncbi.nlm.nih.gov/pubmed/20382026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.03.006 |
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