Residue-Level Prediction of HIV-1 Antibody Epitopes Based on Neutralization of Diverse Viral Strains

Delineation of antibody epitopes at the residue level is key to understanding antigen resistance mutations, designing epitope-specific probes for antibody isolation, and developing epitope-based vaccines. Ideally, epitope residues are determined in the context of the atomic-level structure of the an...

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Bibliographic Details
Main Authors: Chuang, Gwo-Yu, Acharya, Priyamvada, Schmidt, Stephen D., Yang, Yongping, Louder, Mark K., Zhou, Tongqing, Kwon, Young Do, Pancera, Marie, Bailer, Robert T., Doria-Rose, Nicole A., Nussenzweig, Michel C., Mascola, John R., Kwong, Peter D., Georgiev, Ivelin S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753990/
https://ncbi.nlm.nih.gov/pubmed/23843642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00984-13
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