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Rapid development of glycan-specific, broad, and potent anti–HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

It is widely believed that the induction of a broadly neutralizing antibody (bNAb) response will be a critical component of a successful vaccine against HIV. A significant fraction of HIV-infected individuals mount bNAb responses, providing support for the notion that such responses could be elicite...

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Detalhes bibliográficos
Main Authors: Walker, Laura M., Sok, Devin, Nishimura, Yoshiaki, Donau, Olivia, Sadjadpour, Reza, Gautam, Rajeev, Shingai, Masashi, Pejchal, Robert, Ramos, Alejandra, Simek, Melissa D., Geng, Yu, Wilson, Ian A., Poignard, Pascal, Martin, Malcolm A., Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250170/
https://ncbi.nlm.nih.gov/pubmed/22123961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117531108
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