Emergence of gp120 V3 Variants Confers Neutralization Resistance in an R5 Simian-Human Immunodeficiency Virus-Infected Macaque Elite Neutralizer That Targets the N332 Glycan of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein

Neutralization-resistant simian-human immunodeficiency virus AD8 (SHIV(AD8)) variants that emerged in an infected macaque elite neutralizer targeting the human immunodeficiency virus type 1 (HIV-1) gp120 N332 glycan acquired substitutions of critical amino acids in the V3 region rather than losing t...

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Détails bibliographiques
Auteurs principaux: Sadjadpour, Reza, Donau, Olivia K., Shingai, Masashi, Buckler-White, Alicia, Kao, Sandra, Strebel, Klaus, Nishimura, Yoshiaki, Martin, Malcolm A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719840/
https://ncbi.nlm.nih.gov/pubmed/23720719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00878-13
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