Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV

BACKGROUND. Understanding the mechanism(s) by which broadly neutralizing antibodies (bNAbs) emerge naturally following infection is crucial for the development of a protective vaccine against human immunodeficiency virus (HIV). Although previous studies have implicated high viremia and associated im...

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Détails bibliographiques
Publié dans:Clin Infect Dis
Auteurs principaux: Dugast, Anne-Sophie, Arnold, Kelly, Lofano, Giuseppe, Moore, Sarah, Hoffner, Michelle, Simek, Melissa, Poignard, Pascal, Seaman, Michael, Suscovich, Todd J., Pereyra, Florencia, Walker, Bruce D., Lauffenburger, Doug, Kwon, Douglas S., Keele, Brandon F., Alter, Galit
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
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Major Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850011/
https://ncbi.nlm.nih.gov/pubmed/28158448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix057
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