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Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infection
OBJECTIVE: To define the impact of chronic viremia and associated immune activation on B-cell exhaustion in HIV infection. DESIGN: Progressive HIV infection is marked by B-cell anergy and exhaustion coupled with dramatic hypergammaglobulinemia. Although both upregulation of CD95 and loss of CD21 hav...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729211/ https://ncbi.nlm.nih.gov/pubmed/23135171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32835bd1f0 |
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