Conformational Epitope-Specific Broadly Neutralizing Plasma Antibodies Obtained from an HIV-1 Clade C-Infected Elite Neutralizer Mediate Autologous Virus Escape through Mutations in the V1 Loop

Broadly neutralizing antibodies isolated from infected patients who are elite neutralizers have identified targets on HIV-1 envelope (Env) glycoprotein that are vulnerable to antibody neutralization; however, it is not known whether infection established by the majority of the circulating clade C st...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Patil, Shilpa, Kumar, Rajesh, Deshpande, Suprit, Samal, Sweety, Shrivastava, Tripti, Boliar, Saikat, Bansal, Manish, Chaudhary, Nakul Kumar, Srikrishnan, Aylur K., Murugavel, Kailapuri G., Solomon, Suniti, Simek, Melissa, Koff, Wayne C., Goyal, Rajat, Chakrabarti, Bimal K., Bhattacharya, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794693/
https://ncbi.nlm.nih.gov/pubmed/26763999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03090-15
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