Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Broadly neutralizing antibodies (bNAbs), which develop over time in some HIV-1 infected individuals, define critical epitopes for HIV vaccine design. Using a systematic approach, we have examined neutralization breadth in the sera of about 1,800 HIV-1 infected individuals, primarily infected with no...

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Detalhes bibliográficos
Main Authors: Walker, Laura M., Phogat, Sanjay K., Chan-Hui, Po-Ying, Wagner, Denise, Phung, Pham, Goss, Julie L., Wrin, Terri, Simek, Melissa D., Fling, Steven, Mitcham, Jennifer L., Lehrman, Jennifer K., Priddy, Frances H., Olsen, Ole A., Frey, Steven M., Hammond, Phillip W., Kaminsky, Stephen, Zamb, Timothy, Moyle, Matthew, Koff, Wayne C., Poignard, Pascal, Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335270/
https://ncbi.nlm.nih.gov/pubmed/19729618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178746
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