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Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

Broadly neutralizing antibodies (bNAbs), which develop over time in some HIV-1 infected individuals, define critical epitopes for HIV vaccine design. Using a systematic approach, we have examined neutralization breadth in the sera of about 1,800 HIV-1 infected individuals, primarily infected with no...

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書誌詳細
主要な著者: Walker, Laura M., Phogat, Sanjay K., Chan-Hui, Po-Ying, Wagner, Denise, Phung, Pham, Goss, Julie L., Wrin, Terri, Simek, Melissa D., Fling, Steven, Mitcham, Jennifer L., Lehrman, Jennifer K., Priddy, Frances H., Olsen, Ole A., Frey, Steven M., Hammond, Phillip W., Kaminsky, Stephen, Zamb, Timothy, Moyle, Matthew, Koff, Wayne C., Poignard, Pascal, Burton, Dennis R.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335270/
https://ncbi.nlm.nih.gov/pubmed/19729618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1178746
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