Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination

Por Hu, Joyce, Havenar-Daughton, Colin, Crotty, Shane
Publicado em 2013

IL-12 and type-I IFN synergize for IFN-γ production by CD4 T cells, while neither are required for IFN-γ production by CD8 T cells after Listeria monocytogenes infection

Por Way, Sing Sing, Havenar-Daughton, Colin, Kolumam, Ganesh A., Orgun, Nural N., Murali-Krishna, Kaja
Publicado em 2007

A Rapid Strategy to Detect the Recombined Allele in LSL-TβRI(CA) Transgenic Mice

Por Vincent, David F., Kaniewski, Bastien, Powers, Shannon E., Havenar-Daughton, Colin, Marie, Julien C., Wotton, David, Bartholin, Laurent
Publicado em 2010

Early lymphoid responses and germinal center formation correlates with lower viral load set points and better prognosis of SIV infection

Por Hong, Jung Joo, Amancha, Praveen K, Rogers, Kenneth A, Courtney, Cynthia L, Havenar-Daughton, Colin, Crotty, Shane, Ansari, Aftab A, Villinger, Francois
Publicado em 2014

A cytokine-independent approach to identify antigen-specific human germinal center Tfh cells and rare antigen-specific CD4(+) T cells in blood

Por Dan, Jennifer M., Arlehamn, Cecilia S. Lindestam, Weiskopf, Daniela, Antunes, Ricardo da Silva, Havenar-Daughton, Colin, Reiss, Samantha, Brigger, Matthew, Bothwell, Marcella, Sette, Alessandro, Crotty, Shane
Publicado no J Immunol (2016)

Induction of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses in HIV Vaccine Trial Participants Who Subsequently Acquire HIV-1 Infection

Por Horton, Helen, Havenar-Daughton, Colin, Lee, Deborah, Moore, Erin, Cao, Jianhong, McNevin, John, Andrus, Thomas, Zhu, Haiying, Rubin, Abbe, Zhu, Tuofu, Celum, Connie, McElrath, M. Juliana
Publicado em 2006

Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells

Por Reiss, Samantha, Baxter, Amy E., Cirelli, Kimberly M., Dan, Jennifer M., Morou, Antigoni, Daigneault, Audrey, Brassard, Nathalie, Silvestri, Guido, Routy, Jean-Pierre, Havenar-Daughton, Colin, Crotty, Shane, Kaufmann, Daniel E.
Publicado no PLoS One (2017)

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

Por Abbott, Robert K., Lee, Jeong Hyun, Menis, Sergey, Skog, Patrick, Rossi, Meghan, Ota, Takayuki, Kulp, Daniel W., Bhullar, Deepika, Kalyuzhniy, Oleksandr, Havenar-Daughton, Colin, Schief, William R., Nemazee, David, Crotty, Shane
Publicado no Immunity (2017)

Human Circulating PD-1(+)CXCR3(−)CXCR5(+) Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

Por Locci, Michela, Havenar-Daughton, Colin, Landais, Elise, Wu, Jennifer, Kroenke, Mark A., Arlehamn, Cecilia L., Su, Laura F., Cubas, Rafael, Davis, Mark M., Sette, Alessandro, Haddad, Elias K., Poignard, Pascal, Crotty, Shane
Publicado em 2013

Cytokine-independent detection of antigen-specific germinal center T follicular helper (Tfh) cells in immunized non-human primates using a live cell Activation Induced Marker (AIM)...

Por Havenar-Daughton, Colin, Reiss, Samantha M., Carnathan, Diane G., Wu, Jennifer E., Kendric, Kayla, de la Peña, Alba Torrents, Kasturi, Sudhir Pai, Dan, Jennifer M., Bothwell, Marcella, Sanders, Rogier W., Pulendran, Bali, Silvestri, Guido, Crotty, Shane
Publicado no J Immunol (2016)

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

Por Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicado no Nat Commun (2017)

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

Por Jardine, Joseph G., Kulp, Daniel W., Havenar-Daughton, Colin, Sarkar, Anita, Briney, Bryan, Sok, Devin, Sesterhenn, Fabian, Ereño-Orbea, June, Kalyuzhniy, Oleksandr, Deresa, Isaiah, Hu, Xiaozhen, Spencer, Skye, Jones, Meaghan, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, deCamp, Allan C., Julien, Jean-Philippe, Wilson, Ian A., Burton, Dennis R., Crotty, Shane, Schief, William R.
Publicado no Science (2016)

CXCL13 is a plasma biomarker of germinal center activity

Por Havenar-Daughton, Colin, Lindqvist, Madelene, Heit, Antje, Wu, Jennifer E., Reiss, Samantha M., Kendric, Kayla, Bélanger, Simon, Kasturi, Sudhir Pai, Landais, Elise, Akondy, Rama S., McGuire, Helen M., Bothwell, Marcella, Vagefi, Parsia A., Scully, Eileen, Tomaras, Georgia D., Davis, Mark M., Poignard, Pascal, Ahmed, Rafi, Walker, Bruce D., Pulendran, Bali, McElrath, M. Juliana, Kaufmann, Daniel E., Crotty, Shane
Publicado no Proc Natl Acad Sci U S A (2016)

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

Por Landais, Elise, Huang, Xiayu, Havenar-Daughton, Colin, Murrell, Ben, Price, Matt A., Wickramasinghe, Lalinda, Ramos, Alejandra, Bian, Charoan B., Simek, Melissa, Allen, Susan, Karita, Etienne, Kilembe, William, Lakhi, Shabir, Inambao, Mubiana, Kamali, Anatoli, Sanders, Eduard J., Anzala, Omu, Edward, Vinodh, Bekker, Linda-Gail, Tang, Jianming, Gilmour, Jill, Kosakovsky-Pond, Sergei L., Phung, Pham, Wrin, Terri, Crotty, Shane, Godzik, Adam, Poignard, Pascal
Publicado no PLoS Pathog (2016)

Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in T...

Por Kasturi, Sudhir Pai, Kozlowski, Pamela A., Nakaya, Helder I., Burger, Matheus C., Russo, Pedro, Pham, Mathew, Kovalenkov, Yevgeniy, Silveira, Eduardo L. V., Havenar-Daughton, Colin, Burton, Samantha L., Kilgore, Katie M., Johnson, Mathew J., Nabi, Rafiq, Legere, Traci, Sher, Zarpheen Jinnah, Chen, Xuemin, Amara, Rama R., Hunter, Eric, Bosinger, Steven E., Spearman, Paul, Crotty, Shane, Villinger, Francois, Derdeyn, Cynthia A., Wrammert, Jens, Pulendran, Bali
Publicado no J Virol (2017)

Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer

Por Havenar-Daughton, Colin, Carnathan, Diane G., Torrents de la Peña, Alba, Pauthner, Matthias, Briney, Bryan, Reiss, Samantha M., Wood, Jennifer S., Kaushik, Kirti, van Gils, Marit J., Rosales, Sandy, van der Woude, Patricia, Locci, Michela, Le, Khoa M., de Taeye, Steven W., Sok, Devin, Rasheed Mohammed, Ata Ur, Huang, Jessica, Gumber, Sanjeev, Garcia, Anapatricia, Kasturi, Sudhir P., Pulendran, Bali, Moore, John P., Ahmed, Rafi, Seumois, Grégory, Burton, Dennis R., Sanders, Rogier W., Silvestri, Guido, Crotty, Shane
Publicado no Cell Rep (2016)

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

Por Pauthner, Matthias, Havenar-Daughton, Colin, Sok, Devin, Nkolola, Joseph P., Bastidas, Raiza, Boopathy, Archana V., Carnathan, Diane G., Chandrashekar, Abishek, Cirelli, Kimberly M., Cottrell, Christopher A., Eroshkin, Alexey M., Guenaga, Javier, Kaushik, Kirti, Kulp, Daniel W., Liu, Jinyan, McCoy, Laura E., Oom, Aaron L., Ozorowski, Gabriel, Post, Kai W., Sharma, Shailendra K., Steichen, Jon M., de Taeye, Steven W., Tokatlian, Talar, Torrents de la Peña, Alba, Butera, Salvatore T., LaBranche, Celia C., Montefiori, David C., Silvestri, Guido, Wilson, Ian A., Irvine, Darrell J., Sanders, Rogier W., Schief, William R., Ward, Andrew B., Wyatt, Richard T., Barouch, Dan H., Crotty, Shane, Burton, Dennis R.
Publicado no Immunity (2017)