Antibody engineering & therapeutics, the annual meeting of the antibody society December 7–10, 2015, San Diego, CA, USA

Por Pauthner, Matthias, Yeung, Jenny, Ullman, Chris, Bakker, Joost, Wurch, Thierry, Reichert, Janice M., Lund-Johansen, Fridtjof, Bradbury, Andrew R.M., Carter, Paul J., Melis, Joost P.M.
Publicado no MAbs (2016)

Global site-specific analysis of glycoprotein N-glycan processing

Por Cao, Liwei, Diedrich, Jolene K, Ma, Yuanhui, Wang, Nianshuang, Pauthner, Matthias, Park, Sung-Kyu Robin, Delahunty, Claire M, McLellan, Jason S, Burton, Dennis R, Yates, John R, Paulson, James C
Publicado no Nat Protoc (2018)

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

Por Bianchi, Matteo, Turner, Hannah L., Nogal, Bartek, Cottrell, Christopher A., Oyen, David, Pauthner, Matthias, Bastidas, Raiza, Nedellec, Rebecca, McCoy, Laura E., Wilson, Ian A., Burton, Dennis R., Ward, Andrew B., Hangartner, Lars
Publicado no Immunity (2018)

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

Por Zhao, Fangzhu, Joyce, Collin, Burns, Alison, Nogal, Bartek, Cottrell, Christopher A., Ramos, Alejandra, Biddle, Trevor, Pauthner, Matthias, Nedellec, Rebecca, Qureshi, Huma, Mason, Rosemarie, Landais, Elise, Briney, Bryan, Ward, Andrew B., Burton, Dennis R., Sok, Devin
Publicado no Cell Rep (2020)

Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers

Por Carnathan, Diane G., Kaushik, Kirti, Ellebedy, Ali H., Enemuo, Chiamaka A., Gebru, Etse H., Dhadvai, Pallavi, Rasheed, Mohammed Ata Ur, Pauthner, Matthias G., Ozorowski, Gabriel, Ahmed, Rafi, Burton, Dennis R., Ward, Andrew B., Silvestri, Guido, Crotty, Shane, Locci, Michela
Publicado no Front Immunol (2020)

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

Por Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David
Publicado no Science (2015)

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

Por Nogal, Bartek, McCoy, Laura E., van Gils, Marit J., Cottrell, Christopher A., Voss, James E., Andrabi, Raiees, Pauthner, Matthias, Liang, Chi-Hui, Messmer, Terrence, Nedellec, Rebecca, Shin, Mia, Turner, Hannah L., Ozorowski, Gabriel, Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Publicado no Sci Adv (2020)

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

Por Yang, Yuhe R., McCoy, Laura E., van Gils, Marit J., Andrabi, Raiees, Turner, Hannah L., Yuan, Meng, Cottrell, Christopher A., Ozorowski, Gabriel, Voss, James, Pauthner, Matthias, Polveroni, Thomas M., Messmer, Terrence, Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R., Ward, Andrew B.
Publicado no J Virol (2020)

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

Por Sok, Devin, van Gils, Marit J., Pauthner, Matthias, Julien, Jean-Philippe, Saye-Francisco, Karen L., Hsueh, Jessica, Briney, Bryan, Lee, Jeong Hyun, Le, Khoa M., Lee, Peter S., Hua, Yuanzi, Seaman, Michael S., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R.
Publicado no Proc Natl Acad Sci U S A (2014)

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

Por Lee, Jeong Hyun, Andrabi, Raiees, Su, Ching-Yao, Yasmeen, Anila, Julien, Jean-Philippe, Kong, Leopold, Wu, Nicholas C., McBride, Ryan, Sok, Devin, Pauthner, Matthias, Cottrell, Christopher A., Nieusma, Travis, Blattner, Claudia, Paulson, James C., Klasse, Per Johan, Wilson, Ian A., Burton, Dennis R., Ward, Andrew B.
Publicado no Immunity (2017)

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

Por Sok, Devin, Briney, Bryan, Jardine, Joseph G., Kulp, Daniel W., Menis, Sergey, Pauthner, Matthias, Wood, Andrew, Lee, E-Chiang, Le, Khoa M., Jones, Meaghan, Ramos, Alejandra, Kalyuzhniy, Oleksandr, Adachi, Yumiko, Kubitz, Michael, MacPherson, Skye, Bradley, Allan, Friedrich, Glenn A., Schief, William R., Burton, Dennis R.
Publicado no Science (2016)

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer

Por Cao, Liwei, Pauthner, Matthias, Andrabi, Raiees, Rantalainen, Kimmo, Berndsen, Zachary, Diedrich, Jolene K., Menis, Sergey, Sok, Devin, Bastidas, Raiza, Park, Sung-Kyu Robin, Delahunty, Claire M., He, Lin, Guenaga, Javier, Wyatt, Richard T., Schief, William R., Ward, Andrew B., Yates, John R., Burton, Dennis R., Paulson, James C.
Publicado no Nat Commun (2018)

Rectal Acquisition of Simian Immunodeficiency Virus (SIV) SIVmac239 Infection despite Vaccine-Induced Immune Responses against the Entire SIV Proteome

Por Martins, Mauricio A., Gonzalez-Nieto, Lucas, Ricciardi, Michael J., Bailey, Varian K., Dang, Christine M., Bischof, Georg F., Pedreño-Lopez, Nuria, Pauthner, Matthias G., Burton, Dennis R., Parks, Christopher L., Earl, Patricia, Moss, Bernard, Rakasz, Eva G., Lifson, Jeffrey D., Desrosiers, Ronald C., Watkins, David I.
Publicado no J Virol (2020)

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

Por Cao, Liwei, Diedrich, Jolene K., Kulp, Daniel W., Pauthner, Matthias, He, Lin, Park, Sung-Kyu Robin, Sok, Devin, Su, Ching Yao, Delahunty, Claire M., Menis, Sergey, Andrabi, Raiees, Guenaga, Javier, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Yates III, John R., Paulson, James C.
Publicado no Nat Commun (2017)

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

Por Andrabi, Raiees, Pallesen, Jesper, Allen, Joel D., Song, Ge, Zhang, Jinsong, de Val, Natalia, Gegg, Gavin, Porter, Katelyn, Su, Ching-Yao, Pauthner, Matthias, Newman, Amanda, Bouton-Verville, Hilary, Garces, Fernando, Wilson, Ian A., Crispin, Max, Hahn, Beatrice H., Haynes, Barton F., Verkoczy, Laurent, Ward, Andrew B., Burton, Dennis R.
Publicado no Cell Rep (2019)

Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies

Por McCoy, Laura E, van Gils, Marit J, Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E, Kulp, Daniel W, Macauley, Matthew S, Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A, Torres, Jonathan L, Hsueh, Jessica, Schief, William R, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W, Burton, Dennis R
Publicado no Cell Rep (2016)

Infection of Monkeys by Simian-human Immunodeficiency Viruses with Transmitted/ founder Clade C HIV-1 Envelopes

Por Asmal, Mohammed, Luedemann, Corinne, Lavine, Christy L., Mach, Linh V., Balachandran, Harikrishnan, Brinkley, Christie, Denny, Thomas N., Lewis, Mark G., Anderson, Hanne, Pal, Ranajit, Sok, Devin, Le, Khoa, Pauthner, Matthias, Hahn, Beatrice H., Shaw, George M., Seaman, Michael S., Letvin, Norman L., Burton, Dennis R., Sodroski, Joseph G., Haynes, Barton F., Santra, Sampa
Publicado no Virology (2014)

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

Por Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicado no Nat Commun (2017)

A meta-analysis of passive immunization studies shows an association of serum neutralizing antibody titer with protection against SHIV challenge

Por Pegu, Amarendra, Borate, Bhavesh, Huang, Yunda, Pauthner, Matthias G., Hessell, Ann J., Julg, Boris, Doria-Rose, Nicole A., Schmidt, Stephen D., Carpp, Lindsay N., Cully, Michelle D., Chen, Xuejun, Shaw, George M., Barouch, Dan H., Haigwood, Nancy L., Corey, Lawrence, Burton, Dennis R., Roederer, Mario, Gilbert, Peter B., Mascola, John R., Huang, Ying
Publicado no Cell Host Microbe (2019)

A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans

Por Sok, Devin, Pauthner, Matthias, Briney, Bryan, Lee, Jeong Hyun, Saye-Francisco, Karen L., Hsueh, Jessica, Ramos, Alejandra, Le, Khoa M., Jones, Meaghan, Jardine, Joseph G., Bastidas, Raiza, Sarkar, Anita, Liang, Chi-Hui, Shivatare, Sachin S., Wu, Chung-Yi, Schief, William R., Wong, Chi-Huey, Wilson, Ian A., Ward, Andrew B., Zhu, Jiang, Poignard, Pascal, Burton, Dennis R.
Publicado no Immunity (2016)