Functional, Non-Clonal IgM(a)-Restricted B Cell Receptor Interactions with the HIV-1 Envelope gp41 Membrane Proximal External Region

por Verkoczy, Laurent, Moody, M. Anthony, Holl, T. Matt, Bouton-Verville, Hilary, Scearce, Richard M., Hutchinson, Jennifer, Alam, S. Munir, Kelsoe, Garnett, Haynes, Barton F.
Publicado 2009

Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

por Verkoczy, Laurent, Diaz, Marilyn, Holl, T. Matt, Ouyang, Ying-Bin, Bouton-Verville, Hilary, Alam, S. Munir, Liao, Hua-Xin, Kelsoe, Garnett, Haynes, Barton F.
Publicado 2009

Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10()

por Chen, Yao, Zhang, Jinsong, Hwang, Kwan-Ki, Bouton-Verville, Hilary, Xia, Shi-Mao, Newman, Amanda, Ouyang, Ying-Bin, Haynes, Barton F., Verkoczy, Laurent
Publicado 2013

Modulation of Nonneutralizing HIV-1 gp41 Responses by an MHC-Restricted TH Epitope Overlapping Those of Membrane Proximal External Region Broadly Neutralizing Antibodies

por Zhang, Jinsong, Alam, S. Munir, Bouton-Verville, Hilary, Chen, Yao, Newman, Amanda, Stewart, Shelley, Jaeger, Frederick H., Montefiori, David, Dennison, S. Moses, Haynes, Barton F., Verkoczy, Laurent
Publicado 2014

Rescue of HIV-1 Broad Neutralizing Antibody-Expressing B cells in 2F5 V(H)xV(L) Knockin Mice Reveals Multiple Tolerance Controls()

por Verkoczy, Laurent, Chen, Yao, Bouton-Verville, Hilary, Zhang, Jinsong, Diaz, Marilyn, Hutchinson, Jennifer, Ouyang, Ying-Bin, Alam, S. Munir, Holl, T. Matt, Hwang, Kwan-Ki, Kelsoe, Garnett, Haynes, Barton F.
Publicado 2011

Induction of HIV-1 broad neutralizing antibodies in 2F5 knockin mice: selection against MPER-associated autoreactivity limits T-dependent responses

por Verkoczy, Laurent, Chen, Yao, Zhang, Jinsong, Bouton-Verville, Hilary, Newman, Amanda, Lockwood, Bradley, Scearce, Richard M., Montefiori, David C., Dennison, S. Moses, Xia, Shi-Mao, Hwang, Kwan-Ki, Liao, Hua-Xin, Alam, S.Munir, Haynes, Barton F.
Publicado 2013

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template

por Andrabi, Raiees, Pallesen, Jesper, Allen, Joel D., Song, Ge, Zhang, Jinsong, de Val, Natalia, Gegg, Gavin, Porter, Katelyn, Su, Ching-Yao, Pauthner, Matthias, Newman, Amanda, Bouton-Verville, Hilary, Garces, Fernando, Wilson, Ian A., Crispin, Max, Hahn, Beatrice H., Haynes, Barton F., Verkoczy, Laurent, Ward, Andrew B., Burton, Dennis R.
Publicado en Cell Rep (2019)

HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism

por Bradley, Todd, Yang, Guang, Ilkayeva, Olga, Holl, T. Matt, Zhang, Ruijun, Zhang, Jinsong, Santra, Sampa, Fox, Christopher B., Reed, Steve G., Parks, Robert, Bowman, Cindy M., Bouton-Verville, Hilary, Sutherland, Laura L., Scearce, Richard M., Vandergrift, Nathan, Kepler, Thomas B., Moody, M. Anthony, Liao, Hua-Xin, Alam, S. Munir, McLendon, Roger, Everitt, Jeffrey I., Newgard, Christopher B., Verkoczy, Laurent, Kelsoe, Garnett, Haynes, Barton F.
Publicado en J Immunol (2016)

Initiation of immune tolerance–controlled HIV gp41 neutralizing B cell lineages

por Zhang, Ruijun, Verkoczy, Laurent, Wiehe, Kevin, Alam, S. Munir, Nicely, Nathan I., Santra, Sampa, Bradley, Todd, Pemble, Charles W., Zhang, Jinsong, Gao, Feng, Montefiori, David C., Bouton-Verville, Hilary, Kelsoe, Garnett, Larimore, Kevin, Greenberg, Phillip D., Parks, Robert, Foulger, Andrew, Peel, Jessica N., Luo, Kan, Lu, Xiaozhi, Trama, Ashley M., Vandergrift, Nathan, Tomaras, Georgia D., Kepler, Thomas B., Moody, M. Anthony, Liao, Hua-Xin, Haynes, Barton F.
Publicado en Sci Transl Med (2016)

Immune checkpoint modulation enhances HIV-1 antibody induction

por Bradley, Todd, Kuraoka, Masayuki, Yeh, Chen-Hao, Tian, Ming, Chen, Huan, Cain, Derek W., Chen, Xuejun, Cheng, Cheng, Ellebedy, Ali H., Parks, Robert, Barr, Maggie, Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy M., Bouton-Verville, Hilary, Santra, Sampa, Wiehe, Kevin, Lewis, Mark G., Ogbe, Ane, Borrow, Persephone, Montefiori, David, Bonsignori, Mattia, Anthony Moody, M., Verkoczy, Laurent, Saunders, Kevin O., Ahmed, Rafi, Mascola, John R., Kelsoe, Garnett, Alt, Frederick W., Haynes, Barton F.
Publicado en Nat Commun (2020)

Vaccine induction of heterologous tier 2 HIV-1 neutralizing antibodies in animal models

por Saunders, Kevin O., Verkoczy, Laurent K., Jiang, Chuancang, Zhang, Jinsong, Parks, Robert, Chen, Haiyan, Housman, Max, Bouton-Verville, Hilary, Shen, Xiaoying, Trama, Ashley M., Scearce, Richard, Sutherland, Laura, Santra, Sampa, Newman, Amanda, Eaton, Amanda, Xu, Kai, Georgiev, Ivelin S., Joyce, M. Gordon, Tomaras, Georgia D., Bonsignori, Mattia, Reed, Steven G., Salazar, Andres, Mascola, John R., Moody, M. Anthony, Cain, Derek W., Centlivre, Mireille, Zurawski, Sandra, Zurawski, Gerard, Erickson, Harold P., Kwong, Peter D., Alam, S. Munir, Levy, Yves, Montefiori, David C., Haynes, Barton F.
Publicado en Cell Rep (2017)

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations

por Williams, Wilton B., Zhang, Jinsong, Jiang, Chuancang, Nicely, Nathan I., Fera, Daniela, Luo, Kan, Moody, M. Anthony, Liao, Hua-Xin, Alam, S. Munir, Kepler, Thomas B., Ramesh, Akshaya, Wiehe, Kevin, Holland, James A., Bradley, Todd, Vandergrift, Nathan, Saunders, Kevin O., Parks, Robert, Foulger, Andrew, Xia, Shi-Mao, Bonsignori, Mattia, Montefiori, David C., Louder, Mark, Eaton, Amanda, Santra, Sampa, Scearce, Richard, Sutherland, Laura, Newman, Amanda, Bouton-Verville, Hilary, Bowman, Cindy, Bomze, Howard, Gao, Feng, Marshall, Dawn J., Whitesides, John F., Nie, Xiaoyan, Kelsoe, Garnett, Reed, Steven G., Fox, Christopher B., Clary, Kim, Koutsoukos, Marguerite, Franco, David, Mascola, John R., Harrison, Stephen C., Haynes, Barton F., Verkoczy, Laurent
Publicado en Nat Commun (2017)