Rescue of HIV-1 Broad Neutralizing Antibody-Expressing B cells in 2F5 V(H)xV(L) Knockin Mice Reveals Multiple Tolerance Controls()

The HIV-1 broad neutralizing antibody (bnAb) 2F5 has been shown to be poly/self-reactive in vitro, and we previously demonstrated that targeted expression of its VDJ rearrangement alone was sufficient to trigger a profound B cell developmental blockade in 2F5 V(H) knockin (KI) mice, consistent with...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Verkoczy, Laurent, Chen, Yao, Bouton-Verville, Hilary, Zhang, Jinsong, Diaz, Marilyn, Hutchinson, Jennifer, Ouyang, Ying-Bin, Alam, S. Munir, Holl, T. Matt, Hwang, Kwan-Ki, Kelsoe, Garnett, Haynes, Barton F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192533/
https://ncbi.nlm.nih.gov/pubmed/21908739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101633
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados