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Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies

In this brief review, we discuss immune tolerance as a factor that determines the magnitude and quality of serum antibody responses to HIV-1 infection and vaccination in the context of recent work. We propose that many conserved, neutralizing epitopes of HIV-1 are weakly immunogenic because they mim...

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Bibliographic Details
Main Authors: Kelsoe, Garnett, Verkoczy, Laurent, Haynes, Barton F.
Format: Artigo
Language:Inglês
Published: MDPI 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053940/
https://ncbi.nlm.nih.gov/pubmed/24932410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines2010001
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