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Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies
In this brief review, we discuss immune tolerance as a factor that determines the magnitude and quality of serum antibody responses to HIV-1 infection and vaccination in the context of recent work. We propose that many conserved, neutralizing epitopes of HIV-1 are weakly immunogenic because they mim...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053940/ https://ncbi.nlm.nih.gov/pubmed/24932410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines2010001 |
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