Modulation of Nonneutralizing HIV-1 gp41 Responses by an MHC-Restricted TH Epitope Overlapping Those of Membrane Proximal External Region Broadly Neutralizing Antibodies

A goal of HIV-1 vaccine development is to elicit broadly neutralizing antibodies (BnAbs), but current immunization strategies fail to induce BnAbs, and for unknown reasons, often induce non-neutralizing Abs instead. To explore potential host genetic contributions controlling Ab responses to the HIV-...

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Main Authors: Zhang, Jinsong, Alam, S. Munir, Bouton-Verville, Hilary, Chen, Yao, Newman, Amanda, Stewart, Shelley, Jaeger, Frederick H., Montefiori, David, Dennison, S. Moses, Haynes, Barton F., Verkoczy, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936991/
https://ncbi.nlm.nih.gov/pubmed/24465011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302511
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