Vaccine induction of heterologous tier 2 HIV-1 neutralizing antibodies in animal models

The events required for the induction of broad neutralizing antibodies (bnAbs) following HIV-1 envelope (Env) vaccination are unknown, and their induction in animal models as proof-of-concept would be critical. Here, we describe the induction of plasma antibodies capable of neutralizing heterologous...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Saunders, Kevin O., Verkoczy, Laurent K., Jiang, Chuancang, Zhang, Jinsong, Parks, Robert, Chen, Haiyan, Housman, Max, Bouton-Verville, Hilary, Shen, Xiaoying, Trama, Ashley M., Scearce, Richard, Sutherland, Laura, Santra, Sampa, Newman, Amanda, Eaton, Amanda, Xu, Kai, Georgiev, Ivelin S., Joyce, M. Gordon, Tomaras, Georgia D., Bonsignori, Mattia, Reed, Steven G., Salazar, Andres, Mascola, John R., Moody, M. Anthony, Cain, Derek W., Centlivre, Mireille, Zurawski, Sandra, Zurawski, Gerard, Erickson, Harold P., Kwong, Peter D., Alam, S. Munir, Levy, Yves, Montefiori, David C., Haynes, Barton F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777169/
https://ncbi.nlm.nih.gov/pubmed/29281818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.028
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