Vaccine induction of heterologous tier 2 HIV-1 neutralizing antibodies in animal models

The events required for the induction of broad neutralizing antibodies (bnAbs) following HIV-1 envelope (Env) vaccination are unknown, and their induction in animal models as proof-of-concept would be critical. Here, we describe the induction of plasma antibodies capable of neutralizing heterologous...

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Vydáno v:Cell Rep
Hlavní autoři: Saunders, Kevin O., Verkoczy, Laurent K., Jiang, Chuancang, Zhang, Jinsong, Parks, Robert, Chen, Haiyan, Housman, Max, Bouton-Verville, Hilary, Shen, Xiaoying, Trama, Ashley M., Scearce, Richard, Sutherland, Laura, Santra, Sampa, Newman, Amanda, Eaton, Amanda, Xu, Kai, Georgiev, Ivelin S., Joyce, M. Gordon, Tomaras, Georgia D., Bonsignori, Mattia, Reed, Steven G., Salazar, Andres, Mascola, John R., Moody, M. Anthony, Cain, Derek W., Centlivre, Mireille, Zurawski, Sandra, Zurawski, Gerard, Erickson, Harold P., Kwong, Peter D., Alam, S. Munir, Levy, Yves, Montefiori, David C., Haynes, Barton F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777169/
https://ncbi.nlm.nih.gov/pubmed/29281818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.028
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