Very Few Substitutions in a Germ Line Antibody Are Required To Initiate Significant Domain Exchange

Por Huber, Michael, Le, Khoa M., Doores, Katie J., Fulton, Zara, Stanfield, Robyn L., Wilson, Ian A., Burton, Dennis R.
Publicado em 2010

Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies

Por Krumm, Stefanie A., Mohammed, Hajer, Le, Khoa M., Crispin, Max, Wrin, Terri, Poignard, Pascal, Burton, Dennis R., Doores, Katie J.
Publicado no Retrovirology (2016)

Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope

Por Doores, Katie J., Kong, Leopold, Krumm, Stefanie A., Le, Khoa M., Sok, Devin, Laserson, Uri, Garces, Fernando, Poignard, Pascal, Wilson, Ian A., Burton, Dennis R.
Publicado no J Virol (2014)

Correction for Doores et al., Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope

Por Doores, Katie J., Kong, Leopold, Krumm, Stefanie A., Le, Khoa M., Sok, Devin, Laserson, Uri, Garces, Fernando, Poignard, Pascal, Wilson, Ian A., Burton, Dennis R.
Publicado no J Virol (2015)

2G12-Expressing B Cell Lines May Aid in HIV Carbohydrate Vaccine Design Strategies

Por Doores, Katie J., Huber, Michael, Le, Khoa M., Wang, Sheng-Kai, Doyle-Cooper, Colleen, Cooper, Anthony, Pantophlet, Ralph, Wong, Chi-Huey, Nemazee, David, Burton, Dennis R.
Publicado em 2013

Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo

Por Deruaz, Maud, Moldt, Brian, Le, Khoa M., Power, Karen A., Vrbanac, Vladimir D., Tanno, Serah, Ghebremichael, Musie S., Allen, Todd M., Tager, Andrew M., Burton, Dennis R., Luster, Andrew D.
Publicado no J Infect Dis (2016)

Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV

Por Sok, Devin, Doores, Katie J., Briney, Bryan, Le, Khoa M., Saye-Francisco, Karen F., Ramos, Alejandra, Kulp, Daniel W., Julien, Jean-Philippe, Menis, Sergey, Wickramasinghe, Lalinda, Seaman, Michael S., Schief, William R., Wilson, Ian A., Poignard, Pascal, Burton, Dennis R.
Publicado em 2014

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

Por Sok, Devin, van Gils, Marit J., Pauthner, Matthias, Julien, Jean-Philippe, Saye-Francisco, Karen L., Hsueh, Jessica, Briney, Bryan, Lee, Jeong Hyun, Le, Khoa M., Lee, Peter S., Hua, Yuanzi, Seaman, Michael S., Moore, John P., Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Burton, Dennis R.
Publicado no Proc Natl Acad Sci U S A (2014)

A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans

Por Sok, Devin, Pauthner, Matthias, Briney, Bryan, Lee, Jeong Hyun, Saye-Francisco, Karen L., Hsueh, Jessica, Ramos, Alejandra, Le, Khoa M., Jones, Meaghan, Jardine, Joseph G., Bastidas, Raiza, Sarkar, Anita, Liang, Chi-Hui, Shivatare, Sachin S., Wu, Chung-Yi, Schief, William R., Wong, Chi-Huey, Wilson, Ian A., Ward, Andrew B., Zhu, Jiang, Poignard, Pascal, Burton, Dennis R.
Publicado no Immunity (2016)

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

Por Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.
Publicado no Cell (2016)

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

Por Kong, Leopold, Lee, Jeong Hyun, Doores, Katie J., Murin, Charles D., Julien, Jean-Philippe, McBride, Ryan, Liu, Yan, Marozsan, Andre, Cupo, Albert, Klasse, Per-Johan, Hoffenberg, Simon, Caulfield, Michael, King, C. Richter, Hua, Yuanzi, Le, Khoa M., Khayat, Reza, Deller, Marc C., Clayton, Thomas, Tien, Henry, Feizi, Ten, Sanders, Rogier W., Paulson, James C., Moore, John P., Stanfield, Robyn L., Burton, Dennis R., Ward, Andrew B., Wilson, Ian A.
Publicado em 2013

Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer

Por Havenar-Daughton, Colin, Carnathan, Diane G., Torrents de la Peña, Alba, Pauthner, Matthias, Briney, Bryan, Reiss, Samantha M., Wood, Jennifer S., Kaushik, Kirti, van Gils, Marit J., Rosales, Sandy, van der Woude, Patricia, Locci, Michela, Le, Khoa M., de Taeye, Steven W., Sok, Devin, Rasheed Mohammed, Ata Ur, Huang, Jessica, Gumber, Sanjeev, Garcia, Anapatricia, Kasturi, Sudhir P., Pulendran, Bali, Moore, John P., Ahmed, Rafi, Seumois, Grégory, Burton, Dennis R., Sanders, Rogier W., Silvestri, Guido, Crotty, Shane
Publicado no Cell Rep (2016)

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the pre-fusion conformation of the gp41 protein on cleaved Envelope trimers

Por Falkowska, Emilia, Le, Khoa M., Ramos, Alejandra, Doores, Katie J., Lee, Jeong Hyun, Blattner, Claudia, Ramirez, Alejandro, Derking, Ronald, van Gils, Marit J., Liang, Chi-Hui, Mcbride, Ryan, von Bredow, Benjamin, Shivatare, Sachin S., Wu, Chung-Yi, Chan-Hui, Po-Ying, Liu, Yan, Feizi, Ten, Zwick, Michael B., Koff, Wayne C., Seaman, Michael S., Swiderek, Kristine, Moore, John P., Evans, David, Paulson, James C., Wong, Chi-Huey, Ward, Andrew B., Wilson, Ian A., Sanders, Rogier W., Poignard, Pascal, Burton, Dennis R.
Publicado em 2014