Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies

BACKGROUND: Broadly neutralizing antibodies (bnAbs) directed against the mannose-patch on the HIV envelope glycoprotein gp120 have several features that make them desirable targets for vaccine design. The PGT125-131 bnAb family is of particular interest due to its superior breadth and potency. The o...

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Опубликовано в: :Retrovirology
Главные авторы: Krumm, Stefanie A., Mohammed, Hajer, Le, Khoa M., Crispin, Max, Wrin, Terri, Poignard, Pascal, Burton, Dennis R., Doores, Katie J.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736637/
https://ncbi.nlm.nih.gov/pubmed/26837192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0241-5
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