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Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies

BACKGROUND: Broadly neutralizing antibodies (bnAbs) directed against the mannose-patch on the HIV envelope glycoprotein gp120 have several features that make them desirable targets for vaccine design. The PGT125-131 bnAb family is of particular interest due to its superior breadth and potency. The o...

詳細記述

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書誌詳細
出版年:Retrovirology
主要な著者: Krumm, Stefanie A., Mohammed, Hajer, Le, Khoa M., Crispin, Max, Wrin, Terri, Poignard, Pascal, Burton, Dennis R., Doores, Katie J.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4736637/
https://ncbi.nlm.nih.gov/pubmed/26837192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0241-5
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