Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus neutralization profile with a non-sigmoidal slope and a plateau at <100% neutralization. In the current study, we were interested in determini...

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Опубликовано в: :PLoS Pathog
Главные авторы: McCoy, Laura E., Falkowska, Emilia, Doores, Katie J., Le, Khoa, Sok, Devin, van Gils, Marit J., Euler, Zelda, Burger, Judith A., Seaman, Michael S., Sanders, Rogier W., Schuitemaker, Hanneke, Poignard, Pascal, Wrin, Terri, Burton, Dennis R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534392/
https://ncbi.nlm.nih.gov/pubmed/26267277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005110
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