Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus neutralization profile with a non-sigmoidal slope and a plateau at <100% neutralization. In the current study, we were interested in determini...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: McCoy, Laura E., Falkowska, Emilia, Doores, Katie J., Le, Khoa, Sok, Devin, van Gils, Marit J., Euler, Zelda, Burger, Judith A., Seaman, Michael S., Sanders, Rogier W., Schuitemaker, Hanneke, Poignard, Pascal, Wrin, Terri, Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534392/
https://ncbi.nlm.nih.gov/pubmed/26267277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005110
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