Advances in structure-based vaccine design

Por Kulp, Daniel W, Schief, William R
Publicado em 2013

Inhibition of kinesin motility by ADP and phosphate supports a hand-over-hand mechanism

Por Schief, William R., Clark, Rutilio H., Crevenna, Alvaro H., Howard, Jonathon
Publicado em 2004

Residue-Centric Modeling and Design of Saccharide and Glycoconjugate Structures

Por Labonte, Jason W., Adolf-Bryfogle, Jared, Schief, William R., Gray, Jeffrey J.
Publicado no J Comput Chem (2016)

Liquid-Crystalline Collapse of Pulmonary Surfactant Monolayers

Por Schief, William R., Antia, Meher, Discher, Bohdana M., Hall, Stephen B., Vogel, Viola
Publicado em 2003

Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation

Por Smith, Brian C., Underbakke, Eric S., Kulp, Daniel W., Schief, William R., Marletta, Michael A.
Publicado em 2013

High-resolution structure prediction of a circular permutation loop

Por Correia, Bruno E, Holmes, Margaret A, Huang, Po-Ssu, Strong, Roland K, Schief, William R
Publicado em 2011

Elicitation of structure-specific antibodies by epitope scaffolds

Por Ofek, Gilad, Guenaga, F. Javier, Schief, William R., Skinner, Jeff, Baker, David, Wyatt, Richard, Kwong, Peter D.
Publicado em 2010

Reversion of Somatic Mutations of the Respiratory Syncytial Virus-Specific Human Monoclonal Antibody Fab19 Reveal a Direct Relationship Between Association Rate and Neutralizing Po...

Por Bates, John T., Keefer, Christopher J., Utley, Thomas J., Correia, Bruno E., Schief, William R., Crowe, James E.
Publicado em 2013

Design and Characterization of Epitope-Scaffold Immunogens that Present the Motavizumab Epitope from Respiratory Syncytial Virus

Por McLellan, Jason S., Correia, Bruno E., Chen, Man, Yang, Yongping, Graham, Barney S., Schief, William R., Kwong, Peter D.
Publicado em 2011

RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design

Por Huang, Po-Ssu, Ban, Yih-En Andrew, Richter, Florian, Andre, Ingemar, Vernon, Robert, Schief, William R., Baker, David
Publicado em 2011

Role of Complex Carbohydrates in Human Immunodeficiency Virus Type 1 Infection and Resistance to Antibody Neutralization

Por Binley, James M., Ban, Yih-En Andrew, Crooks, Emma T., Eggink, Dirk, Osawa, Keiko, Schief, William R., Sanders, Rogier W.
Publicado em 2010

Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant

Por Guenaga, Javier, Dosenovic, Pia, Ofek, Gilad, Baker, David, Schief, William R., Kwong, Peter D., Karlsson Hedestam, Gunilla B., Wyatt, Richard T.
Publicado em 2011

An HIV-1 Envelope Glycoprotein Trimer with an Embedded IL-21 Domain Activates Human B Cells

Por Isik, Gözde, Chung, Nancy P. Y., van Montfort, Thijs, Menis, Sergey, Matthews, Katie, Schief, William R., Moore, John P., Sanders, Rogier W.
Publicado em 2013

Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development

Por Sampath, Sowmya, Carrico, Chris, Janes, Joel, Gurumoorthy, Sairam, Gibson, Claire, Melcher, Martin, Chitnis, Chetan E., Wang, Ruobing, Schief, William R., Smith, Joseph D.
Publicado em 2013

B cells from knock-in mouse expressing broadly neutralizing HIV antibody b12 carry an innocuous BCR responsive to HIV vaccine candidates

Por Ota, Takayuki, Doyle-Cooper, Colleen, Cooper, Anthony B., Doores, Katherine J., Aoki-Ota, Miyo, Le, Khoa, Schief, William R., Wyatt, Richard T., Burton, Dennis R., Nemazee, David
Publicado em 2013

A Chimeric HIV-1 Envelope Glycoprotein Trimer with an Embedded Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Domain Induces Enhanced Antibody and T Cell Responses

Por van Montfort, Thijs, Melchers, Mark, Isik, Gözde, Menis, Sergey, Huang, Po-Ssu, Matthews, Katie, Michael, Elizabeth, Berkhout, Ben, Schief, William R., Moore, John P., Sanders, Rogier W.
Publicado em 2011

Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10

Por Doyle-Cooper, Colleen, Hudson, Krystalyn E., Cooper, Anthony B., Ota, Takayuki, Skog, Patrick, Dawson, Phillip E., Zwick, Michael B., Schief, William R., Burton, Dennis R., Nemazee, David
Publicado em 2013

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

Por McGuire, Andrew T., Hoot, Sam, Dreyer, Anita M., Lippy, Adriana, Stuart, Andrew, Cohen, Kristen W., Jardine, Joseph, Menis, Sergey, Scheid, Johannes F., West, Anthony P., Schief, William R., Stamatatos, Leonidas
Publicado em 2013

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

Por Abbott, Robert K., Lee, Jeong Hyun, Menis, Sergey, Skog, Patrick, Rossi, Meghan, Ota, Takayuki, Kulp, Daniel W., Bhullar, Deepika, Kalyuzhniy, Oleksandr, Havenar-Daughton, Colin, Schief, William R., Nemazee, David, Crotty, Shane
Publicado no Immunity (2017)

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

Por Pancera, Marie, Majeed, Shahzad, Ban, Yih-En Andrew, Chen, Lei, Huang, Chih-chin, Kong, Leopold, Kwon, Young Do, Stuckey, Jonathan, Zhou, Tongqing, Robinson, James E., Schief, William R., Sodroski, Joseph, Wyatt, Richard, Kwong, Peter D.
Publicado em 2009