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Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation

Nitric oxide (NO) produced by NO synthase (NOS) participates in diverse physiological processes such as vasodilation, neurotransmission, and the innate immune response. Mammalian NOS isoforms are homodimers composed of two domains connected by an intervening calmodulin-binding region. The N-terminal...

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Detalhes bibliográficos
Main Authors: Smith, Brian C., Underbakke, Eric S., Kulp, Daniel W., Schief, William R., Marletta, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780838/
https://ncbi.nlm.nih.gov/pubmed/24003111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313331110
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