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Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation

Nitric oxide (NO) produced by NO synthase (NOS) participates in diverse physiological processes such as vasodilation, neurotransmission, and the innate immune response. Mammalian NOS isoforms are homodimers composed of two domains connected by an intervening calmodulin-binding region. The N-terminal...

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Autores principales: Smith, Brian C., Underbakke, Eric S., Kulp, Daniel W., Schief, William R., Marletta, Michael A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780838/
https://ncbi.nlm.nih.gov/pubmed/24003111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313331110
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