Advances in structure-based vaccine design

Por Kulp, Daniel W, Schief, William R
Publicado em 2013

Salt Bridges: Geometrically Specific, Designable Interactions

Por Donald, Jason E., Kulp, Daniel W., DeGrado, William F.
Publicado em 2011

Generalized Fragment Picking in Rosetta: Design, Protocols and Applications

Por Gront, Dominik, Kulp, Daniel W., Vernon, Robert M., Strauss, Charlie E. M., Baker, David
Publicado em 2011

Nitric oxide synthase domain interfaces regulate electron transfer and calmodulin activation

Por Smith, Brian C., Underbakke, Eric S., Kulp, Daniel W., Schief, William R., Marletta, Michael A.
Publicado em 2013

Design of a switchable eliminase

Por Korendovych, Ivan V., Kulp, Daniel W., Wu, Yibing, Cheng, Hong, Roder, Heinrich, DeGrado, William F.
Publicado em 2011

Structural informatics, modeling and design with an open-source Molecular Software Library (MSL)

Por Kulp, Daniel W., Subramaniam, Sabareesh, Donald, Jason E., Hannigan, Brett T., Mueller, Benjamin K., Grigoryan, Gevorg, Senes, Alessandro
Publicado em 2012

Escape from neutralization by the respiratory syncytial virus-specific neutralizing monoclonal antibody palivizumab is driven by changes in on-rate of binding to the fusion protein

Por Bates, John T., Keefer, Christopher J., Slaughter, James C., Kulp, Daniel W., Schiefd, William R., Crowe, James E.
Publicado em 2014

The Membrane- and Soluble-Protein Helix-Helix Interactome: Similar Geometry via Different Interactions

Por Zhang, Shao-Qing, Kulp, Daniel W., Schramm, Chaim A., Mravic, Marco, Samish, Ilan, DeGrado, William F.
Publicado no Structure (2015)

Consensus motif for integrin transmembrane helix association

Por Berger, Bryan W., Kulp, Daniel W., Span, Lisa M., DeGrado, Jessica L., Billings, Paul C., Senes, Alessandro, Bennett, Joel S., DeGrado, William F.
Publicado em 2010

Small-molecule inhibitors of integrin α(2)β(1) that prevent pathological thrombus formation via an allosteric mechanism

Por Miller, Meredith W., Basra, Sandeep, Kulp, Daniel W., Billings, Paul C., Choi, Sungwook, Beavers, Mary Pat, McCarty, Owen J. T., Zou, Zhiying, Kahn, Mark L., Bennett, Joel S., DeGrado, William F.
Publicado em 2009

Altering the O(2)-Dependent Reactivity of de novo Due Ferri Proteins

Por Reig, Amanda J., Pires, Marcos M., Snyder, Rae Ana, Wu, Yibing, Jo, Hyunil, Kulp, Daniel W., Butch, Susan E., Calhoun, Jennifer R., Szyperski, Thomas, Solomon, Edward I., DeGrado, William F.
Publicado em 2012

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

Por Abbott, Robert K., Lee, Jeong Hyun, Menis, Sergey, Skog, Patrick, Rossi, Meghan, Ota, Takayuki, Kulp, Daniel W., Bhullar, Deepika, Kalyuzhniy, Oleksandr, Havenar-Daughton, Colin, Schief, William R., Nemazee, David, Crotty, Shane
Publicado no Immunity (2017)

Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV

Por Sok, Devin, Doores, Katie J., Briney, Bryan, Le, Khoa M., Saye-Francisco, Karen F., Ramos, Alejandra, Kulp, Daniel W., Julien, Jean-Philippe, Menis, Sergey, Wickramasinghe, Lalinda, Seaman, Michael S., Schief, William R., Wilson, Ian A., Poignard, Pascal, Burton, Dennis R.
Publicado em 2014

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

Por Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David
Publicado no Science (2015)

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

Por Sok, Devin, Briney, Bryan, Jardine, Joseph G., Kulp, Daniel W., Menis, Sergey, Pauthner, Matthias, Wood, Andrew, Lee, E-Chiang, Le, Khoa M., Jones, Meaghan, Ramos, Alejandra, Kalyuzhniy, Oleksandr, Adachi, Yumiko, Kubitz, Michael, MacPherson, Skye, Bradley, Allan, Friedrich, Glenn A., Schief, William R., Burton, Dennis R.
Publicado no Science (2016)

Global site-specific N-glycosylation analysis of HIV envelope glycoprotein

Por Cao, Liwei, Diedrich, Jolene K., Kulp, Daniel W., Pauthner, Matthias, He, Lin, Park, Sung-Kyu Robin, Sok, Devin, Su, Ching Yao, Delahunty, Claire M., Menis, Sergey, Andrabi, Raiees, Guenaga, Javier, Georgeson, Erik, Kubitz, Michael, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Yates III, John R., Paulson, James C.
Publicado no Nat Commun (2017)

Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies

Por McCoy, Laura E, van Gils, Marit J, Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E, Kulp, Daniel W, Macauley, Matthew S, Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A, Torres, Jonathan L, Hsueh, Jessica, Schief, William R, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W, Burton, Dennis R
Publicado no Cell Rep (2016)

Sequential Immunization Elicits Broadly Neutralizing anti-HIV-1 Antibodies in Ig Knock-in Mice

Por Escolano, Amelia, Steichen, Jon M., Dosenovic, Pia, Kulp, Daniel W., Golijanin, Jovana, Sok, Devin, Freund, Natalia T., Gitlin, Alexander D., Oliveira, Thiago, Araki, Tatsuya, Lowe, Sarina, Chen, Spencer T., Heinemann, Jennifer, Yao, Kai-Hui, Georgeson, Erik, Saye-Francisco, Karen L., Gazumyan, Anna, Adachi, Yumiko, Kubitz, Michael, Burton, Dennis R., Schief, William R., Nussenzweig, Michel C.
Publicado no Cell (2016)

Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

Por Kulp, Daniel W., Steichen, Jon M., Pauthner, Matthias, Hu, Xiaozhen, Schiffner, Torben, Liguori, Alessia, Cottrell, Christopher A., Havenar-Daughton, Colin, Ozorowski, Gabriel, Georgeson, Erik, Kalyuzhniy, Oleksandr, Willis, Jordan R., Kubitz, Michael, Adachi, Yumiko, Reiss, Samantha M., Shin, Mia, de Val, Natalia, Ward, Andrew B., Crotty, Shane, Burton, Dennis R., Schief, William R.
Publicado no Nat Commun (2017)

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

Por Jardine, Joseph G., Kulp, Daniel W., Havenar-Daughton, Colin, Sarkar, Anita, Briney, Bryan, Sok, Devin, Sesterhenn, Fabian, Ereño-Orbea, June, Kalyuzhniy, Oleksandr, Deresa, Isaiah, Hu, Xiaozhen, Spencer, Skye, Jones, Meaghan, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, deCamp, Allan C., Julien, Jean-Philippe, Wilson, Ian A., Burton, Dennis R., Crotty, Shane, Schief, William R.
Publicado no Science (2016)