Holes in the glycan shield of the native HIV envelope are a target of trimer-elicited neutralizing antibodies

A major advance in the search for an HIV vaccine has been the development of a near-native Envelope trimer (BG505 SOSIP.664) that can induce robust autologous Tier 2 neutralization. Here, potently neutralizing monoclonal antibodies (nAbs) from rabbits immunized with BG505 SOSIP.664 are shown to reco...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Rep
Main Authors: McCoy, Laura E, van Gils, Marit J, Ozorowski, Gabriel, Messmer, Terrence, Briney, Bryan, Voss, James E, Kulp, Daniel W, Macauley, Matthew S, Sok, Devin, Pauthner, Matthias, Menis, Sergey, Cottrell, Christopher A, Torres, Jonathan L, Hsueh, Jessica, Schief, William R, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W, Burton, Dennis R
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007210/
https://ncbi.nlm.nih.gov/pubmed/27545891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.074
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