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Inhibition of kinesin motility by ADP and phosphate supports a hand-over-hand mechanism

The motor protein kinesin couples a temporally periodic chemical cycle (the hydrolysis of ATP) to a spatially periodic mechanical cycle (movement along a microtubule). To distinguish between different models of such chemical-to-mechanical coupling, we measured the speed of movement of conventional k...

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Detalhes bibliográficos
Main Authors: Schief, William R., Clark, Rutilio H., Crevenna, Alvaro H., Howard, Jonathon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC337027/
https://ncbi.nlm.nih.gov/pubmed/14734813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0304369101
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