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Kinesin Moves by an Asymmetric Hand-Over-Hand Mechanism

Kinesin is a double-headed motor protein that moves along microtubules in 8-nanometer steps. Two broad classes of model have been invoked to explain kinesin movement: hand-over-hand and inchworm. In hand-over-hand models, the heads exchange leading and trailing roles with every step, whereas no such...

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Bibliografiske detaljer
Main Authors: Asbury, Charles L., Fehr, Adrian N., Block, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523256/
https://ncbi.nlm.nih.gov/pubmed/14657506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1092985
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