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On the Origin of Kinesin Limping

Kinesin is a dimeric motor with twin catalytic heads joined to a common stalk. Kinesin molecules move processively along microtubules in a hand-over-hand walk, with the two heads advancing alternately. Recombinant kinesin constructs with short stalks have been found to “limp”, i.e., exhibit alternat...

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Detalhes bibliográficos
Main Authors: Fehr, Adrian N., Gutiérrez-Medina, Braulio, Asbury, Charles L., Block, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749785/
https://ncbi.nlm.nih.gov/pubmed/19751671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.07.004
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