Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

Por McGuire, Andrew T., Hoot, Sam, Dreyer, Anita M., Lippy, Adriana, Stuart, Andrew, Cohen, Kristen W., Jardine, Joseph, Menis, Sergey, Scheid, Johannes F., West, Anthony P., Schief, William R., Stamatatos, Leonidas
Publicado em 2013

Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

Por Jardine, Joseph G., Ota, Takayuki, Sok, Devin, Pauthner, Matthias, Kulp, Daniel W., Kalyuzhniy, Oleksandr, Skog, Patrick D., Thinnes, Theresa C., Bhullar, Deepika, Briney, Bryan, Menis, Sergey, Jones, Meaghan, Kubitz, Mike, Spencer, Skye, Adachi, Yumiko, Burton, Dennis R., Schief, William R., Nemazee, David
Publicado no Science (2015)

Rational HIV immunogen design to target specific germline B cell receptors

Por Jardine, Joseph, Julien, Jean-Philippe, Menis, Sergey, Ota, Takayuki, Kalyuzhniy, Oleksandr, McGuire, Andrew, Sok, Devin, Huang, Po-Ssu, MacPherson, Skye, Jones, Meaghan, Nieusma, Travis, Mathison, John, Baker, David, Ward, Andrew B., Burton, Dennis R., Stamatatos, Leonidas, Nemazee, David, Wilson, Ian A., Schief, William R.
Publicado em 2013

Anti-HIV B Cell Lines As Candidate Vaccine Biosensors(1)

Por Ota, Takayuki, Doyle-Cooper, Colleen, Cooper, Anthony B., Huber, Michael, Falkowska, Emilia, Doores, Katherine J., Hangartner, Lars, Le, Khoa, Sok, Devin, Jardine, Joseph, Lifson, Jeffrey, Wu, Xueling, Mascola, John R., Poignard, Pascal, Binley, James M., Chakrabarti, Bimal K., Schief, William R., Wyatt, Richard T., Burton, Dennis R., Nemazee, David
Publicado em 2012

HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

Por Jardine, Joseph G., Kulp, Daniel W., Havenar-Daughton, Colin, Sarkar, Anita, Briney, Bryan, Sok, Devin, Sesterhenn, Fabian, Ereño-Orbea, June, Kalyuzhniy, Oleksandr, Deresa, Isaiah, Hu, Xiaozhen, Spencer, Skye, Jones, Meaghan, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, deCamp, Allan C., Julien, Jean-Philippe, Wilson, Ian A., Burton, Dennis R., Crotty, Shane, Schief, William R.
Publicado no Science (2016)

A prominent site of antibody vulnerability on HIV envelope incorporates a motif associated with CCR5 binding and its camouflaging glycans

Por Sok, Devin, Pauthner, Matthias, Briney, Bryan, Lee, Jeong Hyun, Saye-Francisco, Karen L., Hsueh, Jessica, Ramos, Alejandra, Le, Khoa M., Jones, Meaghan, Jardine, Joseph G., Bastidas, Raiza, Sarkar, Anita, Liang, Chi-Hui, Shivatare, Sachin S., Wu, Chung-Yi, Schief, William R., Wong, Chi-Huey, Wilson, Ian A., Ward, Andrew B., Zhu, Jiang, Poignard, Pascal, Burton, Dennis R.
Publicado no Immunity (2016)

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knock-In Mice

Por Dosenovic, Pia, von Boehmer, Lotta, Escolano, Amelia, Jardine, Joseph, Freund, Natalia T., Gitlin, Alexander D., McGuire, Andrew T., Kulp, Daniel W., Oliveira, Thiago, Scharf, Louise, Pietzsch, John, Gray, Matthew D., Cupo, Albert, van Gils, Marit J., Yao, Kai-Hui, Liu, Cassie, Gazumyan, Anna, Seaman, Michael S., Björkman, Pamela J., Sanders, Rogier W., Moore, John P., Stamatatos, Leonidas, Schief, William R., Nussenzweig, Michel C.
Publicado no Cell (2015)

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

Por Jardine, Joseph G., Sok, Devin, Julien, Jean-Philippe, Briney, Bryan, Sarkar, Anita, Liang, Chi-Hui, Scherer, Erin A., Henry Dunand, Carole J., Adachi, Yumiko, Diwanji, Devan, Hsueh, Jessica, Jones, Meaghan, Kalyuzhniy, Oleksandr, Kubitz, Michael, Spencer, Skye, Pauthner, Matthias, Saye-Francisco, Karen L., Sesterhenn, Fabian, Wilson, Patrick C., Galloway, Denise M., Stanfield, Robyn L., Wilson, Ian A., Burton, Dennis R., Schief, William R.
Publicado no PLoS Pathog (2016)

Correction: Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

Por Jardine, Joseph G., Sok, Devin, Julien, Jean-Philippe, Briney, Bryan, Sarkar, Anita, Liang, Chi-Hui, Scherer, Erin M., Henry Dunand, Carole J., Adachi, Yumiko, Diwanji, Devan, Hsueh, Jessica, Jones, Meaghan, Kalyuzhniy, Oleksandr, Kubitz, Michael, Spencer, Skye, Pauthner, Matthias, Saye-Francisco, Karen L., Sesterhenn, Fabian, Wilson, Patrick C., Galloway, Denise A., Stanfield, Robyn L., Wilson, Ian A., Burton, Dennis R., Schief, William R.
Publicado no PLoS Pathog (2016)

Proof of principle for epitope-focused vaccine design

Por Correia, Bruno E., Bates, John T., Loomis, Rebecca J., Baneyx, Gretchen, Carrico, Christopher, Jardine, Joseph G., Rupert, Peter, Correnti, Colin, Kalyuzhniy, Oleksandr, Vittal, Vinayak, Connell, Mary J., Stevens, Eric, Schroeter, Alexandria, Chen, Man, MacPherson, Skye, Serra, Andreia M., Adachi, Yumiko, Holmes, Margaret A., Li, Yuxing, Klevit, Rachel E., Graham, Barney S., Wyatt, Richard T., Baker, David, Strong, Roland K., Crowe, James E., Johnson, Philip R., Schief, William R.
Publicado no Nature (2014)

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

Por Briney, Bryan, Sok, Devin, Jardine, Joseph G., Kulp, Daniel W., Skog, Patrick, Menis, Sergey, Jacak, Ronald, Kalyuzhniy, Oleksandr, de Val, Natalia, Sesterhenn, Fabian, Le, Khoa M., Ramos, Alejandra, Jones, Meaghan, Saye-Francisco, Karen L., Blane, Tanya R., Spencer, Skye, Georgeson, Erik, Hu, Xiaozhen, Ozorowski, Gabriel, Adachi, Yumiko, Kubitz, Michael, Sarkar, Anita, Wilson, Ian A., Ward, Andrew B., Nemazee, David, Burton, Dennis R., Schief, William R.
Publicado no Cell (2016)