Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design

An optimal HIV vaccine should induce broadly neutralizing antibodies (bnAbs) that neutralize diverse viral strains and subtypes. However, potent bnAbs develop in only a small fraction of HIV-infected individuals, all contain rare features such as extensive mutation, insertions, deletions, and/or lon...

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Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Jardine, Joseph G., Sok, Devin, Julien, Jean-Philippe, Briney, Bryan, Sarkar, Anita, Liang, Chi-Hui, Scherer, Erin A., Henry Dunand, Carole J., Adachi, Yumiko, Diwanji, Devan, Hsueh, Jessica, Jones, Meaghan, Kalyuzhniy, Oleksandr, Kubitz, Michael, Spencer, Skye, Pauthner, Matthias, Saye-Francisco, Karen L., Sesterhenn, Fabian, Wilson, Patrick C., Galloway, Denise M., Stanfield, Robyn L., Wilson, Ian A., Burton, Dennis R., Schief, William R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999182/
https://ncbi.nlm.nih.gov/pubmed/27560183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005815
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