Structure-based immunogen design — leading the way to the new age of precision vaccines

Por Sesterhenn, Fabian, Bonet, Jaume, Correia, Bruno E
Publicado no Curr Opin Struct Biol (2018)

Mapping the Protein Interaction Landscape for Fully Functionalized Small-Molecule Probes in Human Cells

Por Kambe, Tohru, Correia, Bruno E., Niphakis, Micah J., Cravatt, Benjamin F.
Publicado em 2014

Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering

Por Blackburn, Matthew C., Petrova, Ekaterina, Correia, Bruno E., Maerkl, Sebastian J.
Publicado no Nucleic Acids Res (2016)

rstoolbox - a Python library for large-scale analysis of computational protein design data and structural bioinformatics

Por Bonet, Jaume, Harteveld, Zander, Sesterhenn, Fabian, Scheck, Andreas, Correia, Bruno E.
Publicado no BMC Bioinformatics (2019)

A structural model of an amyloid protofilament of Transthyretin

Por Correia, Bruno E., Loureiro-Ferreira, Nuno, Rodrigues, J. Rui, Brito, Rui M.M.
Publicado em 2006

High-resolution structure prediction of a circular permutation loop

Por Correia, Bruno E, Holmes, Margaret A, Huang, Po-Ssu, Strong, Roland K, Schief, William R
Publicado em 2011

Oligomerization Profile of Human Transthyretin Variants with Distinct Amyloidogenicity

Por Frangolho, Ana, Correia, Bruno E., Vaz, Daniela C., Almeida, Zaida L., Brito, Rui M. M.
Publicado no Molecules (2020)

Reversion of Somatic Mutations of the Respiratory Syncytial Virus-Specific Human Monoclonal Antibody Fab19 Reveal a Direct Relationship Between Association Rate and Neutralizing Po...

Por Bates, John T., Keefer, Christopher J., Utley, Thomas J., Correia, Bruno E., Schief, William R., Crowe, James E.
Publicado em 2013

Global profiling of lysine reactivity and ligandability in the human proteome

Por Hacker, Stephan M., Backus, Keriann M., Lazear, Michael R., Forli, Stefano, Correia, Bruno E., Cravatt, Benjamin F.
Publicado no Nat Chem (2017)

Design and Characterization of Epitope-Scaffold Immunogens that Present the Motavizumab Epitope from Respiratory Syncytial Virus

Por McLellan, Jason S., Correia, Bruno E., Chen, Man, Yang, Yongping, Graham, Barney S., Schief, William R., Kwong, Peter D.
Publicado em 2011

Chemoproteomic profiling and discovery of protein electrophiles in human cells

Por Matthews, Megan L, He, Lin, Horning, Benjamin D, Olson, Erika J, Correia, Bruno E, Yates, John R, Dawson, Philip E, Cravatt, Benjamin F
Publicado no Nat Chem (2016)

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant

Por Bouvignies, Guillaume, Vallurupalli, Pramodh, Hansen, D. Flemming, Correia, Bruno E., Lange, Oliver, Bah, Alaji, Vernon, Robert M., Dahlquist, Frederick W., Baker, David, Kay, Lewis E.
Publicado em 2011

Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A

Por Geiger, Kristina M., Guignard, Daniel, Yang, Che, Bikorimana, Jean-Pierre, Correia, Bruno E., Houard, Sophie, Mkindi, Catherine, Daubenberger, Claudia A., Spertini, François, Corradin, Giampietro, Audran, Régine
Publicado no Front Immunol (2020)

A global map of lipid-binding proteins and their ligandability in cells

Por Niphakis, Micah J., Lum, Kenneth M., Cognetta, Armand B., Correia, Bruno E., Ichu, Taka-Aki, Olucha, Jose, Brown, Steven J., Kundu, Soumajit, Piscitelli, Fabiana, Rosen, Hugh, Cravatt, Benjamin F.
Publicado no Cell (2015)

Rosetta FunFolDes – A general framework for the computational design of functional proteins

Por Bonet, Jaume, Wehrle, Sarah, Schriever, Karen, Yang, Che, Billet, Anne, Sesterhenn, Fabian, Scheck, Andreas, Sverrisson, Freyr, Veselkova, Barbora, Vollers, Sabrina, Lourman, Roxanne, Villard, Mélanie, Rosset, Stéphane, Krey, Thomas, Correia, Bruno E.
Publicado no PLoS Comput Biol (2018)

Ligand and Target Discovery by Fragment-Based Screening in Human Cells

Por Parker, Christopher G., Galmozzi, Andrea, Wang, Yujia J., Correia, Bruno E., Sasaki, Kenji, Joslyn, Christopher M., Kim, Arthur S., Cavallaro, Cullen L., Lawrence, Michael, Johnson, Stephen R., Narvaiza, Iñigo, Saez, Enrique, Cravatt, Benjamin F.
Publicado no Cell (2017)

Proteome-wide covalent ligand discovery in native biological systems

Por Backus, Keriann M., Correia, Bruno E., Lum, Kenneth M., Forli, Stefano, Horning, Benjamin D., González-Páez, Gonzalo E., Chatterjee, Sandip, Lanning, Bryan R., Teijaro, John R., Olson, Arthur J., Wolan, Dennis W., Cravatt, Benjamin F.
Publicado no Nature (2016)

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells

Por Procko, Erik, Berguig, Geoffrey Y., Shen, Betty W., Song, Yifan, Frayo, Shani, Convertine, Anthony J., Margineantu, Daciana, Booth, Garrett, Correia, Bruno E., Cheng, Yuanhua, Schief, William R., Hockenbery, David M., Press, Oliver W., Stoddard, Barry L., Stayton, Patrick S., Baker, David
Publicado em 2014

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

Por Sesterhenn, Fabian, Galloux, Marie, Vollers, Sabrina S., Csepregi, Lucia, Yang, Che, Descamps, Delphyne, Bonet, Jaume, Friedensohn, Simon, Gainza, Pablo, Corthésy, Patricia, Chen, Man, Rosset, Stéphane, Rameix-Welti, Marie-Anne, Éléouët, Jean-François, Reddy, Sai T., Graham, Barney S., Riffault, Sabine, Correia, Bruno E.
Publicado no PLoS Biol (2019)

Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein

Por Mousa, Jarrod J., Sauer, Marion F., Sevy, Alexander M., Finn, Jessica A., Bates, John T., Alvarado, Gabriela, King, Hannah G., Loerinc, Leah B., Fong, Rachel H., Doranz, Benjamin J., Correia, Bruno E., Kalyuzhniy, Oleksandr, Wen, Xiaolin, Jardetzky, Theodore S., Schief, William R., Ohi, Melanie D., Meiler, Jens, Crowe, James E.
Publicado no Proc Natl Acad Sci U S A (2016)