Metabolically labile fumarate esters impart kinetic selectivity to irreversible inhibitors

द्वारा Zaro, Balyn W., Whitby, Landon R., Lum, Kenneth M., Cravatt, Benjamin F.
में प्रकाशित J Am Chem Soc (2016)

Mapping Protein Targets of Bioactive Small Molecules using Lipid-Based Chemical Proteomics

द्वारा Lum, Kenneth M., Sato, Yoshiaki, Beyer, Brittney A., Plaisted, Warren C., Anglin, Justin L., Lairson, Luke L., Cravatt, Benjamin F.
में प्रकाशित ACS Chem Biol (2017)

Multicomponent mapping of boron chemotypes furnishes selective enzyme inhibitors

द्वारा Tan, Joanne, Cognetta III, Armand B., Diaz, Diego B., Lum, Kenneth M., Adachi, Shinya, Kundu, Soumajit, Cravatt, Benjamin F., Yudin, Andrei K.
में प्रकाशित Nat Commun (2017)

Chemical proteomic profiling of human methyltransferases

द्वारा Horning, Benjamin D., Suciu, Radu M., Ghadiri, Darian, Ulanovskaya, Olesya, Matthews, Megan L., Lum, Kenneth M., Backus, Keriann, Brown, Steven J., Rosen, Hugh, Cravatt, Benjamin F.
में प्रकाशित J Am Chem Soc (2016)

Remarkably selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates

द्वारा Chang, Jae Won, Niphakis, Micah J., Lum, Kenneth M., Cognetta, Armand B., Wang, Chu, Matthews, Megan L., Niessen, Sherry, Buczynski, Matthew W., Parsons, Loren H., Cravatt, Benjamin F.
प्रकाशित 2012

A global map of lipid-binding proteins and their ligandability in cells

द्वारा Niphakis, Micah J., Lum, Kenneth M., Cognetta, Armand B., Correia, Bruno E., Ichu, Taka-Aki, Olucha, Jose, Brown, Steven J., Kundu, Soumajit, Piscitelli, Fabiana, Rosen, Hugh, Cravatt, Benjamin F.
में प्रकाशित Cell (2015)

Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator

द्वारा Mizrak, Dogukan, Bayin, N. Sumru, Yuan, Jinzhou, Liu, Zhouzerui, Suciu, Radu M., Niphakis, Micah J., Ngo, Nhi, Lum, Kenneth M., Cravatt, Benjamin F., Joyner, Alexandra L., Sims, Peter A.
में प्रकाशित Cell Rep (2020)

Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan

द्वारा Chen, Alice L., Lum, Kenneth M., Gonzalez, Pablo Lara, Ogasawara, Daisuke, Cognetta, Armand B., To, Alan, Parsons, William H., Simon, Gabriel M., Desai, Arshad, Petrascheck, Michael, Bar-Peled, Liron, Cravatt, Benjamin F.
में प्रकाशित Nat Chem Biol (2019)

Proteome-wide covalent ligand discovery in native biological systems

द्वारा Backus, Keriann M., Correia, Bruno E., Lum, Kenneth M., Forli, Stefano, Horning, Benjamin D., González-Páez, Gonzalo E., Chatterjee, Sandip, Lanning, Bryan R., Teijaro, John R., Olson, Arthur J., Wolan, Dennis W., Cravatt, Benjamin F.
में प्रकाशित Nature (2016)

AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice

द्वारा Erikci Ertunc, Meric, Kok, Bernard P., Parsons, William H., Wang, Justin G., Tan, Dan, Donaldson, Cynthia J., Pinto, Antonio F. M., Vaughan, Joan M., Ngo, Nhi, Lum, Kenneth M., Henry, Cassandra L., Coppola, Aundrea R., Niphakis, Micah J., Cravatt, Benjamin F., Saez, Enrique, Saghatelian, Alan
में प्रकाशित J Biol Chem (2020)

An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers

द्वारा Villa, Genaro R., Hulce, Jonathan J., Zanca, Ciro, Bi, Junfeng, Ikegami, Shiro, Cahill, Gabrielle L., Gu, Yuchao, Lum, Kenneth M., Masui, Kenta, Yang, Huijun, Rong, Xin, Hong, Cynthia, Turner, Kristen M., Liu, Feng, Hon, Gary C., Jenkins, David, Martini, Michael, Armando, Aaron M., Quehenberger, Oswald, Cloughesy, Timothy F., Furnari, Frank B., Cavenee, Webster K., Tontonoz, Peter, Gahman, Timothy C., Shiau, Andrew K., Cravatt, Benjamin F., Mischel, Paul S.
में प्रकाशित Cancer Cell (2016)

An activity-guided map of electrophile-cysteine interactions in primary human T cells

द्वारा Vinogradova, Ekaterina V., Zhang, Xiaoyu, Remillard, David, Lazar, Daniel C., Suciu, Radu M., Wang, Yujia, Bianco, Giulia, Yamashita, Yu, Crowley, Vincent M., Schafroth, Michael A., Yokoyama, Minoru, Konrad, David B., Lum, Kenneth M., Simon, Gabriel M., Kemper, Esther K., Lazear, Michael R., Yin, Sifei, Blewett, Megan M., Dix, Melissa M., Nguyen, Nhan, Shokhirev, Maxim N., Chin, Emily N., Lairson, Luke L., Melillo, Bruno, Schreiber, Stuart L., Forli, Stefano, Teijaro, John R., Cravatt, Benjamin F.
में प्रकाशित Cell (2020)