A Unified Synthetic Strategy to the Cryptocarya Family of Natural Products Exploiting Anion Relay Chemistry (ARC)

od Melillo, Bruno, Smith, Amos B.
Wydane 2013

Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals

od Farrell, Mark, Melillo, Bruno, Smith, Amos B.
Wydane w Angew Chem Int Ed Engl (2015)

An Effective Bifunctional Aldehyde Linchpin for Type II Anion Relay Chemistry: Development and Application to the Synthesis of a C16–C29 Fragment of Rhizopodin

od Melillo, Bruno, Chen, Ming Z., Forestieri, Roberto, Smith, Amos B.
Wydane w Org Lett (2015)

Computational Evaluation of HIV-1 gp120 Conformations of Soluble Trimeric gp140 Structures as Targets for de Novo Docking of First- and Second-Generation Small-Molecule CD4 Mimics

od Moraca, Francesca, Acharya, Kriti, Melillo, Bruno, Smith, Amos B., Chaiken, Irwin, Abrams, Cameron F.
Wydane w J Chem Inf Model (2016)

Ligand-Enabled β-Methylene C(sp(3))−H Arylation of Masked Aliphatic Alcohols

od Xia, Guoqin, Zhuang, Zhe, Liu, Luo-Yan, Schreiber, Stuart L., Melillo, Bruno, Yu, Jin-Quan
Wydane w Angew Chem Int Ed Engl (2020)

Design, Synthesis, and Validation of an Effective, Reusable Silicon-Based Transfer Agent for Room-Temperature Pd-Catalyzed Cross-Coupling Reactions of Aryl and Heteroaryl Chlorides...

od Martinez-Solorio, Dionicio, Melillo, Bruno, Sanchez, Luis, Liang, Yong, Lam, Erwin, Houk, K. N., Smith, Amos B.
Wydane w J Am Chem Soc (2016)

Synthesis of a Bicyclic Azetidine with In Vivo Antimalarial Activity Enabled by Stereospecific, Directed C(sp(3))–H Arylation

od Maetani, Micah, Zoller, Jochen, Melillo, Bruno, Verho, Oscar, Kato, Nobutaka, Pu, Jun, Comer, Eamon, Schreiber, Stuart L.
Wydane w J Am Chem Soc (2017)

Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation

od Jette, Claudia A., Barnes, Christopher O., Kirk, Sharon M., Melillo, Bruno, Smith, Amos B., Bjorkman, Pamela J.
Wydane w Nat Commun (2021)

Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds

od Madani, Navid, Princiotto, Amy M., Zhao, Connie, Jahanbakhshsefidi, Fatemeh, Mertens, Max, Herschhorn, Alon, Melillo, Bruno, Smith, Amos B., Sodroski, Joseph
Wydane w J Virol (2017)

A Small-Molecule CD4-Mimetic Compound Protects Bone Marrow–Liver–Thymus Humanized Mice From HIV-1 Infection

od Princiotto, Amy M, Vrbanac, Vladimir D, Melillo, Bruno, Park, Jongwoo, Tager, Andrew M, Smith, Amos B, Sodroski, Joseph, Madani, Navid
Wydane w J Infect Dis (2018)

Elicitation of Cluster A and Co-Receptor Binding Site Antibodies Are Required to Eliminate HIV-1 Infected Cells

od Beaudoin-Bussières, Guillaume, Prévost, Jérémie, Gendron-Lepage, Gabrielle, Melillo, Bruno, Chen, Junhua, Smith III, Amos B., Pazgier, Marzena, Finzi, Andrés
Wydane w Microorganisms (2020)

Development of an Effective Scalable Enantioselective Synthesis of the HIV-1 Entry Inhibitor BNM-III-170 as the Bis-Trifluoroacetate Salt

od Chen, Junhua, Park, Jun, Kirk, Sharon M., Chen, Hung-Ching, Li, Xiangqin, Lippincott, Daniel J., Melillo, Bruno, Smith, Amos B.
Wydane w Org Process Res Dev (2019)

Synergistic Effects of Stereochemistry and Appendages on the Performance Diversity of a Collection of Synthetic Compounds

od Melillo, Bruno, Zoller, Jochen, Hua, Bruce K., Verho, Oscar, Borghs, Jannik C., Nelson, Shawn D., Maetani, Micah, Wawer, Mathias J., Clemons, Paul A., Schreiber, Stuart L.
Wydane w J Am Chem Soc (2018)

Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines

od Sharma, Manmohan, Malhotra, Nipun, Yogavel, Manickam, Harlos, Karl, Melillo, Bruno, Comer, Eamon, Gonse, Arthur, Parvez, Suhel, Mitasev, Branko, Fang, Francis G., Schreiber, Stuart L., Sharma, Amit
Wydane w Nat Commun (2021)

Stabilizing the HIV-1 Envelope Glycoprotein State 2A Conformation

od Vézina, Dani, Gong, Shang Yu, Tolbert, William D., Ding, Shilei, Nguyen, Dung, Richard, Jonathan, Gendron-Lepage, Gabrielle, Melillo, Bruno, Smith, Amos B., Pazgier, Marzena, Finzi, Andrés
Wydane w J Virol (2021)

Antibody-Dependent Cellular Cytotoxicity against Reactivated HIV-1-Infected Cells

od Lee, Wen Shi, Richard, Jonathan, Lichtfuss, Marit, Smith, Amos B., Park, Jongwoo, Courter, Joel R., Melillo, Bruno N., Sodroski, Joseph G., Kaufmann, Daniel E., Finzi, Andrés, Parsons, Matthew S., Kent, Stephen J.
Wydane w J Virol (2016)

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins

od Herschhorn, Alon, Ma, Xiaochu, Gu, Christopher, Ventura, John D., Castillo-Menendez, Luis, Melillo, Bruno, Terry, Daniel S., Smith, Amos B., Blanchard, Scott C., Munro, James B., Mothes, Walther, Finzi, Andrés, Sodroski, Joseph
Wydane w mBio (2016)

SOSIP Changes Affect Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Conformation and CD4 Engagement

od Alsahafi, Nirmin, Anand, Sai Priya, Castillo-Menendez, Luis, Verly, Myriam Maude, Medjahed, Halima, Prévost, Jérémie, Herschhorn, Alon, Richard, Jonathan, Schön, Arne, Melillo, Bruno, Freire, Ernesto, Smith, Amos B., Sodroski, Joseph, Finzi, Andrés
Wydane w J Virol (2018)

Short Communication: Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein...

od Ding, Shilei, Verly, Myriam M., Princiotto, Amy, Melillo, Bruno, Moody, Anthony M., Bradley, Todd, Easterhoff, David, Roger, Michel, Hahn, Beatrice H., Madani, Navid, Smith, Amos B., Haynes, Barton F., Sodroski, Joseph, Finzi, Andrés
Wydane w AIDS Res Hum Retroviruses (2017)

Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors

od Pacheco, Beatriz, Alsahafi, Nirmin, Debbeche, Olfa, Prévost, Jérémie, Ding, Shilei, Chapleau, Jean-Philippe, Herschhorn, Alon, Madani, Navid, Princiotto, Amy, Melillo, Bruno, Gu, Christopher, Zeng, Xin, Mao, Youdong, Smith, Amos B., Sodroski, Joseph, Finzi, Andrés
Wydane w J Virol (2017)