Effects of the I559P gp41 Change on the Conformation and Function of the Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimer

Por Alsahafi, Nirmin, Debbeche, Olfa, Sodroski, Joseph, Finzi, Andrés
Publicado no PLoS One (2015)

Effects of the SOS (A501C/T605C) and DS (I201C/A433C) Disulfide Bonds on HIV-1 Membrane Envelope Glycoprotein Conformation and Function

Por Nguyen, Hanh T., Alsahafi, Nirmin, Finzi, Andrés, Sodroski, Joseph G.
Publicado no J Virol (2019)

Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity

Por Alsahafi, Nirmin, Richard, Jonathan, Prévost, Jérémie, Coutu, Mathieu, Brassard, Nathalie, Parsons, Matthew S., Kaufmann, Daniel E., Brockman, Mark, Finzi, Andrés
Publicado no J Virol (2017)

Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity

Por Alsahafi, Nirmin, Ding, Shilei, Richard, Jonathan, Markle, Tristan, Brassard, Nathalie, Walker, Bruce, Lewis, George K., Kaufmann, Daniel E., Brockman, Mark A., Finzi, Andrés
Publicado no J Virol (2016)

Targeting the Late Stage of HIV-1 Entry for Antibody-dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region

Por Tolbert, William D., Gohain, Neelakshi, Alsahafi, Nirmin, Van, Verna, Orlandi, Chiara, Ding, Shilei, Martin, Loïc, Finzi, Andrés, Lewis, George K., Ray, Krishanu, Pazgier, Marzena
Publicado no Structure (2017)

Multi-parametric characterization of rare HIV-infected cells using an RNA-flow FISH technique

Por Baxter, Amy E., Niessl, Julia, Fromentin, Rémi, Richard, Jonathan, Porichis, Filippos, Massanella, Marta, Brassard, Nathalie, Alsahafi, Nirmin, Routy, Jean-Pierre, Finzi, Andrés, Chomont, Nicolas, Kaufmann, Daniel E.
Publicado no Nat Protoc (2017)

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity

Por Jin, Steven W., Alsahafi, Nirmin, Kuang, Xiaomei T., Swann, Shayda A., Toyoda, Mako, Göttlinger, Heinrich, Walker, Bruce D., Ueno, Takamasa, Finzi, Andrés, Brumme, Zabrina L., Brockman, Mark A.
Publicado no Cell Rep (2019)

SOSIP Changes Affect Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Conformation and CD4 Engagement

Por Alsahafi, Nirmin, Anand, Sai Priya, Castillo-Menendez, Luis, Verly, Myriam Maude, Medjahed, Halima, Prévost, Jérémie, Herschhorn, Alon, Richard, Jonathan, Schön, Arne, Melillo, Bruno, Freire, Ernesto, Smith, Amos B., Sodroski, Joseph, Finzi, Andrés
Publicado no J Virol (2018)

Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors

Por Pacheco, Beatriz, Alsahafi, Nirmin, Debbeche, Olfa, Prévost, Jérémie, Ding, Shilei, Chapleau, Jean-Philippe, Herschhorn, Alon, Madani, Navid, Princiotto, Amy, Melillo, Bruno, Gu, Christopher, Zeng, Xin, Mao, Youdong, Smith, Amos B., Sodroski, Joseph, Finzi, Andrés
Publicado no J Virol (2017)

Single-cell characterization of viral translation-competent reservoirs in HIV-infected individuals

Por Baxter, Amy E., Niessl, Julia, Fromentin, Rémi, Richard, Jonathan, Porichis, Filippos, Charlebois, Roxanne, Massanella, Marta, Brassard, Nathalie, Alsahafi, Nirmin, Delgado, Gloria-Gabrielle, Routy, Jean-Pierre, Walker, Bruce D., Finzi, Andrés, Chomont, Nicolas, Kaufmann, Daniel E.
Publicado no Cell Host Microbe (2016)

Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity

Por Richard, Jonathan, Veillette, Maxime, Ding, Shilei, Zoubchenok, Daria, Alsahafi, Nirmin, Coutu, Mathieu, Brassard, Nathalie, Park, Jongwoo, Courter, Joel R., Melillo, Bruno, Smith, Amos B., Shaw, George M., Hahn, Beatrice H., Sodroski, Joseph, Kaufmann, Daniel E., Finzi, Andrés
Publicado no EBioMedicine (2015)

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

Por Richard, Jonathan, Pacheco, Beatriz, Gohain, Neelakshi, Veillette, Maxime, Ding, Shilei, Alsahafi, Nirmin, Tolbert, William D., Prévost, Jérémie, Chapleau, Jean-Philippe, Coutu, Mathieu, Jia, Manxue, Brassard, Nathalie, Park, Jongwoo, Courter, Joel R., Melillo, Bruno, Martin, Loïc, Tremblay, Cécile, Hahn, Beatrice H., Kaufmann, Daniel E., Wu, Xueling, Smith, Amos B., Sodroski, Joseph, Pazgier, Marzena, Finzi, Andrés
Publicado no EBioMedicine (2016)

An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity

Por Alsahafi, Nirmin, Bakouche, Nordine, Kazemi, Mohsen, Richard, Jonathan, Ding, Shilei, Bhattacharyya, Sudipta, Das, Durba, Anand, Sai Priya, Prévost, Jérémie, Tolbert, William D., Lu, Hong, Medjahed, Halima, Gendron-Lepage, Gabrielle, Delgado, Gloria Gabrielle Ortega, Kirk, Sharon, Melillo, Bruno, Mothes, Walther, Sodroski, Joseph, Smith, Amos B., Kaufmann, Daniel E., Wu, Xueling, Pazgier, Marzena, Rouiller, Isabelle, Finzi, Andrés, Munro, James B.
Publicado no Cell Host Microbe (2019)

Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.

Por Lu, Maolin, Ma, Xiaochu, Castillo-Menendez, Luis R., Gorman, Jason, Alsahafi, Nirmin, Ermel, Utz, Terry, Daniel S., Chambers, Michael, Peng, Dongjun, Zhang, Baoshan, Zhou, Tongqing, Reichard, Nick, Wang, Kevin, Grover, Jonathan R., Carman, Brennan P., Gardner, Matthew R., Nikic-Spiegel, Ivana, Sugawara, Akihiro, Arthos, James, Lemke, Edward A., Smith, Amos B., Farzan, Michael, Abrams, Cameron, Munro, James B., McDermott, Adrian B., Finzi, Andrés, Kwong, Peter D., Blanchard, Scott C., Sodroski, Joseph G., Mothes, Walther
Publicado no Nature (2019)