Targeting the Late Stage of HIV-1 Entry for Antibody-dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region

Antibodies can impact HIV-1 infection in multiple ways including antibody-dependent cellular cytotoxicity (ADCC), a correlate of protection observed in the RV144 vaccine trial. One of the most potent ADCC-inducing epitopes on HIV-1 Env is recognized by the C11 antibody. Here we present the crystal s...

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Publicado no:Structure
Main Authors: Tolbert, William D., Gohain, Neelakshi, Alsahafi, Nirmin, Van, Verna, Orlandi, Chiara, Ding, Shilei, Martin, Loïc, Finzi, Andrés, Lewis, George K., Ray, Krishanu, Pazgier, Marzena
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677539/
https://ncbi.nlm.nih.gov/pubmed/29056481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.09.009
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