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Effects of the I559P gp41 Change on the Conformation and Function of the Human Immunodeficiency Virus (HIV-1) Membrane Envelope Glycoprotein Trimer

The mature human immunodeficiency virus (HIV-1) envelope glycoprotein (Env) trimer is produced by proteolytic cleavage of a precursor and consists of three gp120 exterior and three gp41 transmembrane subunits. The metastable Env complex is induced to undergo conformational changes required for virus...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Alsahafi, Nirmin, Debbeche, Olfa, Sodroski, Joseph, Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4388519/
https://ncbi.nlm.nih.gov/pubmed/25849367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122111
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