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Contribution of the gp120 V3 loop to envelope glycoprotein trimer stability in primate immunodeficiency viruses

The V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 exterior envelope glycoprotein (Env) becomes exposed after CD4 binding and contacts the coreceptor to mediate viral entry. Prior to CD4 engagement, a hydrophobic patch located at the tip of the V3 loop stabilizes the non-covalent a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Virology
Prif Awduron: Bowder, Dane, Hollingsead, Haley, Durst, Kate, Hu, Duoyi, Wei, Wenzhong, Wiggins, Joshua, Medjahed, Halima, Finzi, Andrés, Sodroski, Joseph, Xiang, Shi-Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Academic Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6053598/
https://ncbi.nlm.nih.gov/pubmed/29936340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.06.005
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