A Twin-Cysteine Motif in the V2 Region of gp120 Is Associated with SIV Envelope Trimer Stabilization

The V1 and V2 variable regions of the primate immunodeficiency viruses contribute to the trimer association domain of the gp120 exterior envelope glycoprotein. A pair of V2 cysteine residues at 183 and 191 (“twin cysteines”) is present in several simian immunodeficiency viruses, human immunodeficien...

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Bibliographic Details
Main Authors: Bohl, Christopher, Bowder, Dane, Thompson, Jesse, Abrahamyan, Levon, Gonzalez-Ramirez, Sandra, Mao, Youdong, Sodroski, Joseph, Wood, Charles, Xiang, Shi-hua
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3720275/
https://ncbi.nlm.nih.gov/pubmed/23936006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069406
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